ReviewJournal of molecular histology2021
Salivary gland proteins alterations in the diabetic milieu.
Review in Journal of molecular histology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The trial behind it
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Who cites it
25 citing papers in PubMed, 34 citations in OpenAlex.
- Salivary gland function and redox status in young adult male rats treated with the psychostimulant short-release methylphenidate.Odontology · 2026Article
- Salivary protein macromolecules as diagnostic and therapeutic biomarkers linking oral health and neurodegenerative diseases-emerging mechanisms and future perspectives.Inflammopharmacology · 2026Review
- Estrogen deficiency due to type 2 diabetes induced hyposalivation in female mice by promoting inflammation in the salivary glands.Odontology · 2026Article
- Clinical studies on the effect of type 1 diabetes on oral health in children and adolescents aged 6-17 years. A literature review.Medicine and pharmacy reports · 2026Review
- Bioinformatics-led identification of pathophysiological hallmark genes in diabesotension via graph clustering method.Journal of diabetes and metabolic disorders · 2025Article
- Exploring the impact of advanced glycation end products on diabetic salivary gland dysfunctions.Glycoconjugate journal · 2025Review
- Exploring the Landscape of Salivary Gland Disorders: A Comprehensive Bibliometric Analysis.Journal of maxillofacial and oral surgery · 2025Article
- Innovative Dual Therapy: Magnesium Oxide Nanoparticles and Royal Jelly for Parotid Gland Protection in Diabetic Male Rats.International journal of nanomedicine · 2025Article
- Molecular Mechanisms Underlying the Therapeutic Potential of Plant-Based α-Amylase Inhibitors for Hyperglycemic Control in Diabetes.Current diabetes reviews · 2025Review
- Lower Serum IL-10 Linked to Oral Manifestations in Diabetes Patients.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- The Effect of Vitamin E, Β-Carotene, and Acidophilus Probiotics on The Salivary Gland Flow Rate in Streptozotocin-Induced Diabetes in Rats: An in-vivo Study.Clinical, cosmetic and investigational dentistry · 2025Article
- Photobiomodulation for diabetes and its complications: a review of general presentation, mechanisms and efficacy.Annals of medicine · 2024Review
- Antox targeting AGE/RAGE cascades to restore submandibular gland viability in rat model of type 1 diabetes.Scientific reports · 2024Article
- P2X7R and P2X4R expression of mice submandibular gland in high-fat diet/streptozotocin-induced type 2 diabetes.Scientific reports · 2024Article
- Current developments and opportunities of pluripotent stem cells-based therapies for salivary gland hypofunction.Frontiers in cell and developmental biology · 2024Review
- Melatonin Action in Type 2 Diabetic Parotid Gland and Dental Pulp: In Vitro and Bioinformatic Findings.International journal of environmental research and public health · 2023Article
- The Prevalence of Xerostomia in Older Thai Individuals with Type II Diabetes Mellitus and Its Association with Type of Toothpaste and Oral Functions: A Cross-Sectional Study Using Questionnaires.Geriatrics (Basel, Switzerland) · 2023Article
- Changes in salivary biomarkers associated with periodontitis and diabetic neuropathy in individuals with type 1 diabetes.Scientific reports · 2022Article
- High Expression Level of α2-3-Linked Sialic Acids on Salivary Glycoproteins of Breastfeeding Women May Help to Protect Them from Avian Influenza Virus Infection.Molecules (Basel, Switzerland) · 2022Article
- Heat Shock Proteins Alterations in Rheumatoid Arthritis.International journal of molecular sciences · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Salivary glands are considered the chief exocrine glands of the mouth and physiologically contribute to the maintenance of the homeostasis of the oral cavity. They consist of the parotid, submandibular and sublingual glands, which come in pairs and are collectively called the major glands, and the minor glands, which are much smaller and are dispersed throughout the buccal cavity. Salivary glands are distinguished by their size, amount of saliva secretion and their location in the oral cavity. Salivary glands pathophysiology has been a subject of interest in various worldwide metabolic disorders, including diabetes mellitus. Diabetes mellitus (DM), a global health concern, with a pathological imprint involved in vasculature, promotes microvascular and macrovascular complications among which periodontitis ranks sixth. Indeed, DM has also been directly associated with oral health lesions. Specifically, salivary glands in the context of diabetes have been a focal point of study and emphasis in the research field. There is evidence that relates salivary secretion content and diabetes progression. In this review, we present all the reported evidence of the deregulation of specific salivary proteins associated with the progression of diabetes in parallel with changes in salivary gland morphology, cellular architecture, and salivary secretion and composition more generally.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.