Evidence map›Paper›PMID 34212259›Full record

ArticleDysphagia2022

Per-oral Endoscopic Myotomy with Division of Septum (D-POEM) in Epiphrenic Esophageal Diverticula: Outcomes at a Median Follow-Up of Two Years.

Zaheer Nabi, Radhika Chavan, Shujaath Asif, Mohan Ramchandani, Jahangeer Basha, Santosh Darisetty, Rajesh Goud, Rama Kotla, D Nageshwar Reddy

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In one paragraph

Article in Dysphagia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Endoscopic esophageal reconstruction in epiphrenic diverticulum: septotomy-free diverticulectomy and suturing.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Zaheer NabiAsian Institute of Gastroenterology, 6-3-661, Hyderabad, 500082, India. zaheernabi1978@gmail.com.ORCID http://orcid.org/0000-0003-2713-4781
Radhika ChavanAsian Institute of Gastroenterology, 6-3-661, Hyderabad, 500082, India.
Shujaath AsifAsian Institute of Gastroenterology, 6-3-661, Hyderabad, 500082, India.
Mohan RamchandaniAsian Institute of Gastroenterology, 6-3-661, Hyderabad, 500082, India.
Jahangeer BashaAsian Institute of Gastroenterology, 6-3-661, Hyderabad, 500082, India.
Santosh DarisettyAsian Institute of Gastroenterology, 6-3-661, Hyderabad, 500082, India.
Rajesh GoudAsian Institute of Gastroenterology, 6-3-661, Hyderabad, 500082, India.
Rama KotlaAsian Institute of Gastroenterology, 6-3-661, Hyderabad, 500082, India.
D Nageshwar ReddyAsian Institute of Gastroenterology, 6-3-661, Hyderabad, 500082, India.
Asian Institute of Gastroenterology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal epiphrenic diverticula (EED) are rare pulsion-type outpouchings at the lower end of esophagus. Traditionally, surgery has been performed in EED. More recently, per-oral endoscopic myotomy with septotomy (D-POEM) has emerged as an option in these cases. In this study, we aim to determine the efficacy and safety of D-POEM in cases with EED. The data of cases who underwent D-POEM in cases with EED from March 2013 to Nov 2020 were analyzed, retrospectively. The primary outcome of the study was clinical success. Secondary outcomes included technical success, procedure duration, reflux esophagitis, and adverse events. 13 patients (males 9, 48.07 ± 17.55 years) with EED underwent D-POEM during the study period. Median size of the EED was 45 mm (range 25-70). Associated esophageal motility disorder was found in 10 (76.9%) cases including type II achalasia (3), type I (3), hypercontractile esophagus (2), and unspecified (2). Technical success was achieved in 12 (92.3%) cases. Median length of total and gastric myotomies were 10 cm (range 6-20) and 3 cm (1-3), respectively. At a median follow-up of 25 months, clinical success was achieved in 84.6% cases. Mean integrated relaxation pressures reduced significantly after POEM procedure (25.80 ± 13.24 vs 9.40 ± 3.10, p = 0.001). There was one major adverse event requiring surgical intervention. D-POEM is an effective procedure in cases with EED. Long-term follow-up studies are required to ascertain the durability of response in these cases.

Indexed as

Diverticulum, EsophagealMyotomyNatural Orifice Endoscopic SurgeryEsophageal Sphincter, LowerFollow-Up StudiesHumansMaleRetrospective StudiesTreatment OutcomeDiverticulumEpiphrenicEsophagusPer-oral endoscopic myotomy

Identifiers

PMID34212259
OpenAlexW3176790749

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.