ArticleNeuroradiology2021
Altered brain structural topological properties and its correlations with clinical characteristics in episodic migraine without aura.
Article in Neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Brain network properties in chronic pain-a systematic review and meta-analysis of graph-based connectivity metrics.Frontiers in neuroscience · 2025Pooled it
- Resting-state electroencephalography and magnetoencephalography in migraine-a systematic review and meta-analysis.The journal of headache and pain · 2024Pooled it
- Integrated anatomical and functional connectivity mapping in episodic migraine: a spectral graph theory approach.Scientific reports · 2026Article
- Altered Topology of Brain Structural Network in Patients With Migraine Without Aura: A Structural MRI Study.European journal of pain (London, England) · 2025Article
- Changes in the functional brain networks and graph theory analysis of patients with epilepsy and comorbid migraine without aura.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Association between white matter microstructural and functional abnormalities and clinical characteristics in migraine without aura: a mediation analysis.Frontiers in neurology · 2025Article
- Disrupted topologic efficiency of white matter structural connectome in migraine: a graph-based connectomics study.The journal of headache and pain · 2024Article
- Involvement of the cerebellum in structural connectivity enhancement in episodic migraine.The journal of headache and pain · 2024Article
- Shifts in structural connectome organization in the limbic and sensory systems of patients with episodic migraine.The journal of headache and pain · 2024Article
- Right-to-left shunt-associated brain functional changes in migraine: evidences from a resting-state FMRI study.Frontiers in human neuroscience · 2024Article
- Increased hippocampal efficiency is associated with greater headache frequency in adolescents with chronic headache.Cerebral cortex communications · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
purposeTo investigate the topological alterations of the whole-brain white matter structural networks in episodic migraine (EM) without aura.
methodsForty-five EM patients without aura and 35 age- and sex-matched healthy controls were registered, and underwent diffusion tensor MRI acquisition at interictal. Graph theory-based analyses were then performed for the characterization of brain structural network properties. Pearson correlation analysis was performed on each network metric between the EM patients and healthy controls.
resultsThe EM patients exhibited abnormal global network properties and local network topology that were characterized by more strongly integrated, more efficient, and faster information transferring. These network differences were widely located in the occipital, temporal, and parietal regions. Additionally, the local efficient of global parameters showed positive correlation with visual analogue scale, and along with prolonging disease duration, the nodal efficiency would be reduced, and the nodal shortest path length would be increased. Headache Impact Test version 6 scores have negative correlation with the nodal shortest path length, and positive correlations with the nodal efficiency.
conclusionThe results indicate that EM patients had aberrant topological structure and make a better understanding of structural connectivity in EM; it may provide imaging evidence for clinical study of migraine pathogenesis.
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