Evidence map›Paper›PMID 34211808›Full record

ArticleCureus2021

ST-Elevation Myocardial Infarction in a 23-Year-Old Female: The Mystery of Thrombus Formation.

Billal H Sikandar, Scott Butler, Anusha Battula, Rajendra Shetty

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Inferior Wall STEMI in a Young Patient-A Sequela of Phentermine and Smoking.Journal of community hospital internal medicine perspectives · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Billal H SikandarInternal Medicine, University of Maryland Capital Region Medical Center, Largo, USA.
Scott ButlerCardiology, University of Maryland Medical Center, Baltimore, USA.
Anusha BattulaInternal Medicine, University of Maryland Capital Region Medical Center, Largo, USA.
Rajendra ShettyInterventional Cardiology, University of Maryland Capital Region Medical Center, Largo, USA.
Capital Region Medical Center · USUniversity of Maryland, Baltimore · USUniversity of Maryland Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute ST-elevation myocardial infarction (STEMI) is rarely seen in young adults, however, when encountered, the underlying cause is either a genetic condition leading to early-onset coronary artery disease (CAD), an acquired pro-thrombotic condition, or an idiopathic condition like spontaneous coronary artery dissection (SCAD). Our case describes a healthy 23-year-old female who presented with sudden onset severe angina and was found to have a laminated thrombus in the left anterior descending coronary artery (LAD), with no evidence of intraluminal dissection or plaque rupture. Although the underlying etiology of thrombus formation remains unknown, coronavirus disease 2019 (COVID-19) related thrombotic event is the prime suspect. In addition, another culprit that cannot be excluded is phentermine-induced coronary vasospasm, a commercially available medication for weight loss. This report addresses current literature on acute coronary syndromes in young adults and reviews the potential etiologies for coronary artery thrombosis, which led to a near-fatal acute coronary syndrome in our patient.

Indexed as

asymptomatic covid-19coronary artery thrombuscoronary artery vasospasmcovid-19 outbreakcovid and hearthyper coagulable statephenterminesar-cov 2 infectionspontaneous coronary artery thrombosisst-segment elevation myocardial infarction (stemi)

Identifiers

PMID34211808
PMCPMC8236289
OpenAlexW3167002282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.