Evidence map›Paper›PMID 34211746›Full record

ArticleCurrent health sciences journal

PRP Enriched with Hyaluronic Acid -PRP from Rat Protocol and Method of Preparation.

Elena-Alexandra Marinescu, Oliviu Nica, Enio Ilinoiu, Anca Cojocaru, Alina Alexandra Negrilă, Marius Eugen Ciurea

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In one paragraph

Article in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Elena-Alexandra MarinescuDepartment of Plastic Surgery, University of Medicine and Pharmacy of Craiova.
Oliviu NicaDepartment of Plastic Surgery, University of Medicine and Pharmacy of Craiova.
Enio IlinoiuPlastic surgery Clinic, Emergency County Hospital of Craiova.
Anca CojocaruDepartment of Plastic Surgery, University of Medicine and Pharmacy of Craiova.
Alina Alexandra NegrilăPlastic surgery Clinic, Emergency County Hospital of Craiova.
Marius Eugen CiureaDepartment of Plastic Surgery, University of Medicine and Pharmacy of Craiova.
University of Medicine and Pharmacy of Craiova · ROCounty Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Observing the positive effects of PRP (platelet-rich plasma) used in various pathologies, both in traumatology, orthopedics, sports medicine, and in plastic and reconstructive surgery, we decided to develop an improved product, using granular hyaluronic acid. The paper aims at establishing a protocol for obtaining PRP enriched with hyaluronic acid, which can be used in the current practice of treatment of skin defects, safely, with minimal side effects and limited possible, but to provide a shorter healing period as compared to native, "free" healing. The experiment aims to find an effective and rapid method of healing wounds with skin defects, by using a local adjuvant (PRP enriched with hyaluronic acid), which is available to any plastic surgeon. Following the combination of PRP with granular hyaluronic acid, we obtained a product that macroscopically has a gelatinous, viscous consistency, with a good adhesion to the tissues. The potential benefits of this experiment could be the basis for the development of treatment protocols for various pathologies, which result in wounds with skin defects, the most important aspect being the shortening of the classic healing period.

Indexed as

hyaluronic acidPlatelet-rich plasmapreparationprotocolrat

Identifiers

PMID34211746
PMCPMC8200601
OpenAlexW3176166459

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.