Evidence map›Paper›PMID 34211724›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Family planning in Argentinian women with multiple sclerosis: An important yet seldom approached issue.

Ricardo Alonso, Liliana Patrucco, Berenice Silva, Cecilia Quarracino, María Barbara Eizaguirre, Carlos Vrech, Pablo López, Edgar Carnero Contentti, Norma Deri, Adriana Carrá and 11 more

Open access · goldAbstract read
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 10 institutions in 1 country.

Ricardo AlonsoServicio de Neurología, Sanatorio Güemes, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0001-9955-8343
Liliana PatruccoCentro de Esclerosis Múltiple de Buenos Aires, Buenos Aires, Argentina.
Berenice SilvaCentro Universitario de Esclerosis Múltiple, Hospital Dr. J. M. Ramos Mejía, Facultad de Medicina - UBA, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0001-5866-2419
Cecilia QuarracinoServicio de Neurología. Instituto Alfredo Lanari, Hospital Universitario, Buenos Aires, Argentina.
María Barbara EizaguirreCentro Universitario de Esclerosis Múltiple, Hospital Dr. J. M. Ramos Mejía, Facultad de Medicina - UBA, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0002-7817-2772
Carlos VrechDepartamento de Enfermedades desmielinizantes, Sanatorio Allende, Córdoba, Argentina.
Pablo LópezNeuroimmunology Unit, Department of Neuroscience, Hospital Alemán, Buenos Aires, Argentina.
Edgar Carnero ContenttiNeuroimmunology Unit, Department of Neuroscience, Hospital Alemán, Buenos Aires, Argentina.
Norma DeriCentro de Investigaciones Diabaid, Buenos Aires, Argentina.
Adriana CarráSección de Enfermedades Desmielinizantes, Hospital Británico, Buenos Aires, Argentina.
Aníbal ChercorffSección de Enfermedades Desmielinizantes, Hospital Británico, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0002-8645-6134
Verónica TkachukSección de Esclerosis Múltiple y Enfermedades Desmielinizantes, Servicio de Neurología, Hospital de Clínicas José de San Martín, Buenos Aires, Argentina.
María Eugenia BalbuenaSección de Esclerosis Múltiple y Enfermedades Desmielinizantes, Servicio de Neurología, Hospital de Clínicas José de San Martín, Buenos Aires, Argentina.
Juan Pablo PettinicchiNeuroimmunology Unit, Department of Neuroscience, Hospital Alemán, Buenos Aires, Argentina.
Darío TavoliniINECO Neurociencias Oroño, Rosario, Santa Fe, Argentina.
Andrés BarbozaHospital Central de Mendoza, Mendoza, Argentina.
Juan I RojasCentro de Esclerosis Múltiple de Buenos Aires, Buenos Aires, Argentina.
Edgardo CristianoCentro de Esclerosis Múltiple de Buenos Aires, Buenos Aires, Argentina.
Luciana LázaroServicio de Neurología, Sanatorio Güemes, Buenos Aires, Argentina.
Orlando GarceaCentro Universitario de Esclerosis Múltiple, Hospital Dr. J. M. Ramos Mejía, Facultad de Medicina - UBA, Buenos Aires, Argentina.
Nora Fernández LiguoriServicio de Neurología, Sanatorio Güemes, Buenos Aires, Argentina.
Hospital Ramos Mejía · ARHospital Alemán · ARHelios Salud · ARHospital de Clínicas "José de San Martín" · ARInstituto de Neurología Cognitiva · ARFundacion Allende · ARHospital Británico de Buenos Aires · ARHospital Universitario Austral · ARInstituto Universitario Hospital Italiano · ARUniversity of Mendoza · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to assess family planning (FP) among women with multiple sclerosis (WwMS).

methodsWe invited 604 WwMS to answer a survey focused on FP: a) Temporal relationship between pregnancy and the diagnosis of multiple sclerosis; b) History of FP; c) Childbearing desire; d) Information on family planning. Comparisons between pregnancy and not pregnancy after MS, as well as, planned and unplanned pregnancy were analyzed. Multivariate and univariate analyses were used to assess the impact of independent variables and FP.

result428 (71.7%) WwMS completed the survey. A 19.1% got pregnant after MS diagnosis and we evaluated FP in the last pregnancy, 56.1% patients had a planned pregnancy. Professional addressing FP (OR = 0.27, 95%-CI 0.08-0.92, p = 0.03) and non-injection drug treatment before pregnancy (OR = 2.88, 95%-CI 1.01-8.21, p = 0.047) were independent predictors of unplanned pregnancy in our multivariate model. Among WwMS ≤ 40 years, 48.7% had future childbearing desire. Young age (p < 0.001), PDDS <3 (p = 0.018), disease duration <5 years (p = 0.02), not childbearing before MS diagnosis (p < 0.001) and neurologist addressing family planning (p = 0.01) were significantly associated with childbearing desire.

conclusionsThis research highlights that pregnancy remains an important concern among WwMS.

Indexed as

family planningMultiple sclerosispregnancy

Identifiers

PMID34211724
PMCPMC8216353
OpenAlexW3175020307

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.