ArticleF1000Research2021
Risk factors for mortality in hospitalized patients with COVID-19 from three hospitals in Peru: a retrospective cohort study.
Article in F1000Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- Biomarkers for predicting COVID-19 mortality: A study at Sulianti Saroso Infectious Disease Hospital, Indonesia.Narra J · 2025Article
- Prevalence of post-traumatic stress disorder in Peruvian military: a cross-sectional study.Frontiers in psychiatry · 2025Article
- Laboratory biomarkers associated with COVID-19 mortality among inpatients in a Peruvian referral hospital.Heliyon · 2024Article
- Predicting Mortality for COVID-19 Patients Admitted to an Emergency Department Using Early Warning Scores in Poland.Healthcare (Basel, Switzerland) · 2024Article
- Predictors of hospital length of stay and mortality among COVID-19 inpatients during 2020-2021 in Hormozgan Province of Iran: A retrospective cohort study.Health science reports · 2023Article
- Depression and anxiety in peruvian military personnel during the pandemic context: a cross-sectional study.BMC public health · 2023Article
- Factors Associated with COVID-19 Death in a High-Altitude Peruvian Setting during the First 14 Months of the Pandemic: A Retrospective Multicenter Cohort Study in Hospitalized Patients.Tropical medicine and infectious disease · 2023Article
- Prevalence and Factors Associated with Eating Disorders in Military First Line of Defense against COVID-19: A Cross-Sectional Study during the Second Epidemic Wave in Peru.International journal of environmental research and public health · 2023Article
- Clinical Characteristics and Outcomes of COVID-19 Patients in Mazandaran Province, Iran.Tanaffos · 2023Article
- Clinical-epidemiologic variation in patients treated in the first and second wave of COVID-19 in Lambayeque, Peru: A cluster analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Article
- Analysis of Excess All-Cause Mortality and COVID-19 Mortality in Peru: Observational Study.Tropical medicine and infectious disease · 2022Article
- Prescription Patterns of Drugs Given to Hospitalized COVID-19 Patients: A Cross-Sectional Study in Colombia.Antibiotics (Basel, Switzerland) · 2022Article
- Developing a Comprehensive Multidimensional Wellbeing Index Based on What People Value: An Application to a Middle-Income Country.Applied research in quality of life · 2022Article
- Mortality and associated risk factors in patients hospitalized due to COVID-19 in a Peruvian reference hospital.PloS one · 2022Article
- The Neutrophil-to-Lymphocyte Ratio and the Platelet-to-Lymphocyte Ratio as Predictors of Mortality in Older Adults Hospitalized with COVID-19 in Peru.Disease markers · 2022Article
- Antibiotic Use and Fatal Outcomes among Critically Ill Patients with COVID-19 in Tacna, Peru.Antibiotics (Basel, Switzerland) · 2021Article
- Predictors of Mortality Among Hospitalized COVID-19 Patients at a Tertiary Care Hospital in Ethiopia.Infection and drug resistance · 2021Article
- Comorbidities associated with COVID-19 mortality in adults in Lima, Peru: a retrospective cohort study.Revista peruana de medicina experimental y salud publicaArticle
- Post-traumatic Stress Disorder and Resilience in Medical Students: A Multicenter Study from 13 Latin American Countries.Chronic stress (Thousand Oaks, Calif.)Article
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Authors and funding
8 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeru was one of the countries with the highest COVID-19 mortality worldwide during the first stage of the pandemic. It is then relevant to evaluate the risk factors for mortality in patients hospitalized for COVID-19 in three hospitals in Peru in 2020, from March to May, 2020. Methods: We carried out a retrospective cohort study. The population consisted of patients from three Peruvian hospitals hospitalized for a diagnosis of COVID-19 during the March-May 2020 period. Independent sociodemographic variables, medical history, symptoms, vital functions, laboratory parameters and medical treatment were evaluated. In-hospital mortality was assessed as the outcome. We performed Cox regression models (crude and adjusted) to evaluate risk factors for in-hospital mortality. Hazard ratios (HR) with their respective 95% confidence intervals (95% CI) were calculated. Results: We analyzed 493 hospitalized adults; 72.8% (n=359) were male and the mean age was 63.3 ± 14.4 years. COVID-19 symptoms appeared on average 7.9 ± 4.0 days before admission to the hospital, and the mean oxygen saturation on admission was 82.6 ± 13.8. While 67.6% (n=333) required intensive care unit admission, only 3.3% (n=16) were admitted to this unit, and 60.2% (n=297) of the sample died. In the adjusted regression analysis, it was found that being 60 years old or older (HR=1.57; 95% CI: 1.14-2.15), having two or more comorbidities (HR=1.53; 95% CI: 1.10-2.14), oxygen saturation between 85-80% (HR=2.52; 95% CI: 1.58-4.02), less than 80% (HR=4.59; 95% CI: 3.01-7.00), and being in the middle (HR=1.65; 95% CI: 1.15-2.39) and higher tertile (HR=2.18; 95% CI: 1.51-3.15) of the neutrophil-to-lymphocyte ratio, increased the risk of mortality. Conclusions: The risk factors found agree with what has been described in the literature and allow the identification of vulnerable groups in whom monitoring and early identification of symptoms should be prioritized in order to reduce mortality.
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