Evidence map›Paper›PMID 34211689›Full record

ArticleTherapeutic advances in drug safety2021

Attitudes of ambulatory care older Nepalese patients towards deprescribing and predictors of their willingness to deprescribe.

Shakti Shrestha, Roshan Giri, Hari Prasad Sapkota, Siddhartha Sharma Danai, Ahsan Saleem, Shreeshab Devkota, Sagar Shrestha, Bhojraj Adhikari, Arjun Poudel

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Article in Therapeutic advances in drug safety, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shakti ShresthaSchool of Pharmacy, The University of Queensland, Pharmacy Australia Centre of Excellence, Level 4, 20 Cornwall Street, Woolloongabba, QLD 4102, Australia.ORCID https://orcid.org/0000-0003-0344-091X
Roshan GiriDepartment of Pharmacy, Shree Medical and Technical College, Bharatpur, Chitwan, Nepal.
Hari Prasad SapkotaDepartment of Pharmacy, Shree Medical and Technical College, Bharatpur, Chitwan, Nepal.
Siddhartha Sharma DanaiDepartment of Pharmacy, Shree Medical and Technical College, Bharatpur, Chitwan, Nepal.
Ahsan SaleemSchool of Pharmacy, The University of Queensland, Brisbane, QLD 4102, Australia.
Shreeshab DevkotaDepartment of Pharmacy, Shree Medical and Technical College, Bharatpur, Chitwan, Nepal.
Sagar ShresthaDepartment of Pharmacy, Shree Medical and Technical College, Bharatpur, Chitwan, Nepal.
Bhojraj AdhikariDepartment of Internal Medicine, Bharatpur District Hospital, Bharatpur, Chitwan, Nepal.
Arjun PoudelSchool of Clinical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD 4000, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOlder adults continue to receive potentially inappropriate medications necessitating the need for medication optimization, by deprescribing. To ensure a holistic approach to deprescribing, it is essential to understand the perception of older adults towards deprescribing. This study aimed to assess the attitude of older ambulatory patients towards deprescribing and to identify factors predicting their willingness to deprescribe.

methodsA cross-sectional survey was conducted in central Nepal between March and September 2019 among 385 older ambulatory care patients (aged ⩾65 years) who were taking at least one regular medicine. The perception of patients towards deprescribing was assessed using the revised Patients' Attitudes Towards Deprescribing (rPATD) questionnaire

resultsThe median [interquartile range (IQR)] age of patients was 72 (8) years. Nearly three in five patients (64.9%) had hypertension, with 11.2% having polypharmacy. More than half of the patients (57.4%) would be willing to stop one or more of their regular medicines if their doctor said it was possible to do so. Regression analysis showed that age [odds ratio (OR) 0.946; 95% CI 0.913, 0.981;

conclusionOne in two older ambulatory care patients in Nepal would be willing to have one or more of their medicines deprescribed. The factors predicting their willingness to deprescribe are their age and concerns about stopping medicines. Clinicians should consider discussing the possibility of deprescribing with older patients for the prevention of potential medication-related harms. PLAIN LANGUAGE SUMMARY: What do older Nepalese patients think about withdrawal or dose reduction of an inappropriate medication?

Indexed as

deprescribingolder adultspolypharmacypotentially inappropriate medicationrPATD

Identifiers

PMID34211689
PMCPMC8216397

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.