ArticleTherapeutic advances in musculoskeletal disease2021
Increased risk of valvular heart disease in patients with ankylosing spondylitis: a nationwide population-based longitudinal cohort study.
Article in Therapeutic advances in musculoskeletal disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Valve Abnormalities, Risk Factors for Heart Valve Disease and Valve Replacement Surgery in Spondyloarthritis. A Systematic Review of the Literature.Frontiers in cardiovascular medicine · 2021Pooled it
- Immune-mediated inflammatory diseases and the risk of valvular heart disease: a Mendelian randomization study.Clinical rheumatology · 2024Article
- Association of ankylosing spondylitis with cardiovascular disease: a bidirectional two-sample mendelian randomization study.Frontiers in genetics · 2024Article
- Effects of ankylosing spondylitis on cardiovascular disease: aMendelian randomization study.Frontiers in genetics · 2024Article
- No evidence of a causal relationship between ankylosing spondylitis and cardiovascular disease: a two-sample Mendelian randomization study.Frontiers in cardiovascular medicine · 2023Article
- Case Report: A Rare Manifestation of Pulmonary Arterial Hypertension in Ankylosing Spondylitis.Journal of personalized medicine · 2022Article
- Factors Associated with the Risk of Major Adverse Cardiovascular Events in Patients with Ankylosing Spondylitis: A Nationwide, Population-Based Case-Control Study.International journal of environmental research and public health · 2022Article
- Multimodality Evaluation of Aortic Insufficiency and Aortitis in Rheumatologic Diseases.Frontiers in cardiovascular medicine · 2022Review
- Audiometric evaluation of bone conduction thresholds reveals subclinical sensorineural hearing loss in patients with ankylosing spondylitis and psoriatic arthritis.Brazilian journal of otorhinolaryngologyArticle
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsWe aimed to evaluate the risk of valvular heart disease (VHD) among patients with ankylosing spondylitis (AS).
methodsThis was a population-based cohort study utilizing the Longitudinal Health Insurance Research Database of the National Health Insurance in Taiwan. Patients with and without coding of newly diagnosed AS from 1999 to 2013 were assigned to the AS and non-AS groups, respectively. Primary outcome was the incidental risk of VHD. Multiple Cox regression was used to estimate the adjusted hazard ratio of VHD. Subgroup analysis and sensitivity tests were also conducted.
resultsThe AS group included 3780 patients, and 22,680 matched subjects without an AS diagnosis were identified as controls. The AS group had an increased risk of VHD compared with non-AS controls (adjusted hazard ratio: 1.63; 95% confidence interval: 1.43-1.86;
conclusionPatients with AS had a significant risk of VHD compared to non-AS controls in this population-based cohort study. Screening for VHD may be needed in caring patients with AS. We suggest that echocardiography may be performed when patients are diagnosed with AS.
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