Evidence map›Paper›PMID 34211521›Full record

ArticleJornal vascular brasileiro2020

Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2.

Marcos Antonio Bonacorso Manhanelli, Eliud Garcia Duarte, Jamil Victor de Oliveira Mariuba, Fábio Linardi, José Augusto Costa, Julio Cesar Gali, Winston Bonetti Yoshida, Julio Cesar Gali

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Jornal vascular brasileiro, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Acute Limb Ischemia in COVID-19: A Systematic Review.The International journal of angiology : official publication of the International College of Angiology, Inc · 2023
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Marcos Antonio Bonacorso ManhanelliPontifícia Universidade Católica de São Paulo - PUC-SP, Sorocaba, SP, Brasil.ORCID 0000-0003-2203-5717
Eliud Garcia DuarteHospital Santa Mônica, Cirurgia Vascular e Endovascular, Vila Velha, ES, Brasil.ORCID 0000-0003-1504-6303
Jamil Victor de Oliveira MariubaPontifícia Universidade Católica de São Paulo - PUC-SP, Sorocaba, SP, Brasil.ORCID 0000-0002-8229-9848
Fábio LinardiPontifícia Universidade Católica de São Paulo - PUC-SP, Sorocaba, SP, Brasil.ORCID 0000-0002-7519-0254
José Augusto CostaPontifícia Universidade Católica de São Paulo - PUC-SP, Sorocaba, SP, Brasil.
Julio Cesar GaliPontifícia Universidade Católica de São Paulo - PUC-SP, Sorocaba, SP, Brasil.ORCID 0000-0003-2369-6322
Winston Bonetti YoshidaUniversidade Estadual Paulista "Júlio de Mesquita Filho" - UNESP, Botucatu, SP, Brasil.ORCID 0000-0002-2921-3777
Julio Cesar GaliJJMED, Sorocaba, SP, Brasil.ORCID 0000-0002-4960-9656
Pontifícia Universidade Católica de São Paulo · BRUniversidade de Sorocaba · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade Vila Velha · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current coronavirus pandemic has already taken a great toll globally, causing massive morbidity and mortality. One of its severe forms is a thrombophilic state that can damage several systems. This article reports the case of 60-year-old female patient who presented with mild flu symptoms, which turned out to be a SARS-CoV2 infection, and ended up developing arterial thrombosis with limb ischemia in a private care hospital in Sorocaba, São Paulo, Brazil. Considering this progression, we decided to intervene with low molecular weight heparin and Alprostadil, achieving a good clinical outcome. Our description aims to identify key points and clinical signs that offer evidence of the therapeutic window and a treatment option for coagulatory presentations of COVID-19.

Indexed as

arterial thrombosisCOVID-19heparinlimb ischemiathromboembolism

Identifiers

PMID34211521
PMCPMC8218011
OpenAlexW3110097568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.