Evidence map›Paper›PMID 34211305›Full record

ArticleJournal of blood medicine2021

Different Types of Minor Blood Group Incompatibility Causing Haemolytic Disease of Neonates in one of the National Children's Medical Centre in China.

Mingchun Lin, Meixiu Liu, Shulian Zhang, Chao Chen, Jin Wang

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in Journal of blood medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05617612 (Neonatal Alloantibodies in Cord Blood for Early Detection of Hemolytic Disease of Newborn), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05617612 unknown statusnot on this mapstarted 2022, after this paper: background citation

Neonatal Alloantibodies in Cord Blood for Early Detection of Hemolytic Disease of Newborn

TypeobservationalSponsorAssiut UniversityRan2022 to 2024Enrolled400ConditionsHDN - Hemolytic Disease of the Newborn
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Neonatal JkBMC pediatrics · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. A case of naturally occurring anti-DiAsian journal of transfusion science
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mingchun LinNeonatal Department, Children's Hospital of Fudan University, Shanghai, 201102, People's Republic of China.
Meixiu LiuBlood Bank, Children's Hospital of Fudan University, Shanghai, 201102, People's Republic of China.
Shulian ZhangNeonatal Department, Children's Hospital of Fudan University, Shanghai, 201102, People's Republic of China.
Chao ChenNeonatal Department, Children's Hospital of Fudan University, Shanghai, 201102, People's Republic of China.
Jin WangNeonatal Department, Children's Hospital of Fudan University, Shanghai, 201102, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo review the neonatal cases with different types of minor blood group incompatible haemolytic diseases in China, and to improve the clinical understanding and management. MATERIALS AND

methodsSeven cases from January, 1st, 2013 to December 31st, 2019 were searched out and reviewed retrospectively. All clinical data and laboratory findings were collected.

resultsThere were totally seven cases enrolled including three cases of MNS, three of Diego, and one of Kidd combined with Rh, anti-RhE incompatibility. Among the seven cases, two had intrauterine transfusion, two underwent exchange transfusion, five received intravenous immune globulin, five cases developed anaemia, and three of them had transfusion. But among them, only four were found to have positive antibody screening and three were confirmed HDN with antibody types antenatally.

conclusionThe clinical presentation is diverse. Antibody screening followed by the technique of peak systolic velocity in the fetal middle cerebral artery (MCA-PSV) helps to filter out the severe cases.

Indexed as

alloimmunizationDiego blood groupHDNKidd blood groupMNS blood groupneonatal haemolytic disease

Identifiers

PMID34211305
PMCPMC8240843

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Registered trials

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