Evidence map›Paper›PMID 34211257›Full record

ReviewProceedings (Baylor University. Medical Center)2021

Evidence-based approach to early outpatient treatment of SARS-CoV-2 (COVID-19) infection.

J Drew Payne, Kimberly Sims, Cynthia Peacock, Tanis Welch, Ruth E Berggren

Abstract readReview
In one paragraph

Review in Proceedings (Baylor University. Medical Center), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

J Drew PayneDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas.ORCID https://orcid.org/0000-0002-9708-2641
Kimberly SimsDepartment of Internal Medicine, Houston Methodist Primary Care Group, Pearland, Texas.
Cynthia PeacockDepartment of Internal Medicine, Baylor College of Medicine, Houston, Texas.
Tanis WelchDepartment of Pharmacy, UMC Health System, Lubbock, Texas.
Ruth E BerggrenCenter for Medical Humanities & Ethics, UT Health San Antonio, San Antonio, Texas.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Misinformation and promotion of well-intended but disproved therapies for COVID-19 have plagued evidence-based shared decision-making throughout the COVID-19 pandemic. In times of crisis, clinicians may feel that their strong inclination to prescribe potentially harmful, unproven therapies on behalf of their patients is supported by beneficence. Clinicians should mindfully identify and avoid commission bias during this pandemic, especially as more data have accumulated to assist with clinically sound decision-making. We describe a more evidence-based approach to treatment of early outpatient COVID-19, stressing the availability of Food and Drug Administration emergency use authorization therapies and considering plausibly beneficial, nonprescription supplements that are generally regarded as safe.

Indexed as

colchicineCOVID-19evidence-basedivermectinmelatoninoutpatient therapySARS-CoV-2

Identifiers

PMID34211257
PMCPMC8182819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.