ArticleNature microbiology2021
A slicing mechanism facilitates host entry by plant-pathogenic Phytophthora.
Article in Nature microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Mechanisms and Advances in Plant Lipid Regulatory Responses Under Biotic and Abiotic Stress.Genes · 2026Review
- Oomycete plant pathogens: biology, pathogenesis and emerging control strategies.Nature reviews. Microbiology · 2026Review
- The diverse roles of host membranes in plant-microbe interactions.PLoS pathogens · 2026Article
- Thermochromic hydrogel with high transmittance modulation and fast response for flexible smart windows.Communications materials · 2025Article
- Revealing real-time 3D in vivo pathogen dynamics in plants by label-free optical coherence tomography.Nature communications · 2024Article
- GhMPK9-GhRAF39_1-GhWRKY40a Regulates the GhERF1b- and GhABF2-Mediated Pathways to Increase Cotton Disease Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Cell geometry regulates tissue fracture.Nature communications · 2023Article
- A molecular mechanosensor for real-time visualization of appressorium membrane tension in Magnaporthe oryzae.Nature microbiology · 2023Article
- Genome-wide association analysis reveals a novel pathway mediated by a dual-TIR domain protein for pathogen resistance in cotton.Genome biology · 2023Article
- Hierarchically Structured Deformation-Sensing Mechanochromic Pigments.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Exogenous double-stranded RNA inhibits the infection physiology of rust fungi to reduce symptoms in planta.Molecular plant pathology · 2023Article
- Molecular sensors reveal the mechano-chemical response ofCell surface (Amsterdam, Netherlands) · 2022Article
- An actin mechanostat ensures hyphal tip sharpness inScience advances · 2022Article
- 2021 in review.Nature microbiology · 2021Article
- Phytophthora cuts into plant hosts.Nature reviews. Microbiology · 2021Article
- Plant killers make the cut.Nature microbiology · 2021Article
- Uncovering the Role of Metabolism in Oomycete-Host Interactions Using Genome-Scale Metabolic Models.Frontiers in microbiology · 2021Review
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10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phytophthora species, classified as oomycetes, are among the most destructive plant pathogens worldwide and pose a substantial threat to food security. Plant pathogens have developed various methods to breach the cuticle and walls of plant cells. For example, plant-pathogenic fungi use a 'brute-force' approach by producing a specialized and fortified invasion organ to generate invasive pressures. Unlike in fungi, the biomechanics of host invasion in oomycetes remains poorly understood. Here, using a combination of surface-deformation imaging, molecular-fracture sensors and modelling, we find that Phytophthora infestans, Phytophthora palmivora and Phytophthora capsici slice through the plant surface to gain entry into host tissues. To distinguish this mode of entry from the brute-force approach of fungi that use appressoria, we name this oomycete entry without appressorium formation 'naifu' invasion. Naifu invasion relies on polarized, non-concentric, force generation onto the surface at an oblique angle, which concentrates stresses at the site of invasion to enable surface breaching. Measurements of surface deformations during invasion of artificial substrates reveal a polarized mechanical geometry that we describe using a mathematical model. We confirm that the same mode of entry is used on real hosts. Naifu invasion uses actin-mediated polarity, surface adherence and turgor generation to enable Phytophthora to invade hosts without requiring specialized organs or vast turgor generation.
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