ArticleMolecular psychiatry2021
Patterns of brain asymmetry associated with polygenic risks for autism and schizophrenia implicate language and executive functions but not brain masculinization.
Article in Molecular psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Linking Polygenic Risk of Schizophrenia to Variation in Magnetic Resonance Imaging Brain Measures: A Comprehensive Systematic Review.Schizophrenia bulletin · 2024Pooled it
- Fixation Task: A Simple Eye Movement Task Reveals an Impairment in Schizophrenia.Schizophrenia bulletin · 2026Article
- Molecular and cellular correlates of human cortical lateralization.Communications biology · 2026Article
- Individualized cortical thickness asymmetry in autism spectrum disorder and schizophrenia.Molecular psychiatry · 2026Article
- Recent developments in imaging transcriptomics for psychiatric disorders.Psychoradiology · 2026Review
- Hemispheric Asymmetry in the Genetic Overlap between Schizophrenia and White Matter Microstructure.Cyborg and bionic systems (Washington, D.C.) · 2026Article
- Polygenic risk for schizophrenia is associated with white matter microstructure, cognitive and mental health.Schizophrenia (Heidelberg, Germany) · 2025Article
- Sex Differences in the role of Additive Genetic Variants in Autism: A Systematic Review.medRxiv : the preprint server for health sciences · 2025Article
- Systematic Review and Meta-Analysis: Phenotypic Correlates of the Autism Polygenic Score.JAACAP open · 2025Article
- Motor dysfunction, social context and early prodromal features of psychosis: historical acumen, developmental pathobiology and early intervention.Schizophrenia (Heidelberg, Germany) · 2025Article
- The molecular and cellular underpinnings of human brain lateralization.bioRxiv : the preprint server for biology · 2025Article
- Associations between fMRI signal amplitude, hemispheric asymmetry, and task performance.Communications biology · 2025Article
- Systematic bias in surface area asymmetry measurements from automatic cortical parcellations.Brain structure & function · 2025Article
- Polygenic scores for autism are associated with reduced neurite density in adults and children from the general population.Molecular psychiatry · 2025Article
- From genetics and cerebral asymmetry, through motor dysfunction intrinsic to psychosis, to early intervention: elaborating the seminal contributions of Timothy J. Crow.Psychological medicine · 2025Article
- The Balance in the Head: How Developmental Factors Explain Relationships Between Brain Asymmetries and Mental Diseases.Brain sciences · 2025Review
- Perinatal adversities as a common factor underlying the association between atypical laterality and neurodevelopmental disorders: A developmental perspective.Psychophysiology · 2024Review
- Shared Genetic Determinants of Schizophrenia and Autism Spectrum Disorder Implicate Opposite Risk Patterns: A Genome-Wide Analysis of Common Variants.Schizophrenia bulletin · 2024Article
- Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness.Communications biology · 2024Article
- Shared atypical spontaneous brain activity pattern in early onset schizophrenia and autism spectrum disorders: evidence from cortical surface-based analysis.European child & adolescent psychiatry · 2024Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Autism spectrum disorder (ASD) and schizophrenia have been conceived as partly opposing disorders in terms of systemizing vs. empathizing cognitive styles, with resemblances to male vs. female average sex differences. Left-right asymmetry of the brain is an important aspect of its organization that shows average differences between the sexes and can be altered in both ASD and schizophrenia. Here we mapped multivariate associations of polygenic risk scores for ASD and schizophrenia with asymmetries of regional cerebral cortical surface area, thickness, and subcortical volume measures in 32,256 participants from the UK Biobank. Polygenic risks for the two disorders were positively correlated (r = 0.08, p = 7.13 × 10
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.