ArticleScientific reports2021
Results from a large cross-sectional study assessing Chlamydia trachomatis, Ureaplasma spp. and Mycoplasma hominis urogenital infections in patients with primary infertility.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 41 citations in OpenAlex.
- Association of Ureaplasma urealyticum with lifestyle factors and semen parameters: results from a cross-sectional study in 2668 males.Asian journal of andrology · 2026Article
- Worldwide prevalence ofNew microbes and new infections · 2026Review
- Detection and antimicrobial susceptibility of genital mycoplasmas in women and men, with 23S rRNA and parC mutation analysis in Mycoplasma genitalium.Scientific reports · 2026Article
- Antibiotic Exposure and Early Reproductive Outcomes of In Vitro Fertilization (IVF) in a Chinese Couple-Based Preconception Cohort.Environment & health (Washington, D.C.) · 2026Article
- The Impact ofOpen forum infectious diseases · 2026Review
- Immunological Causes of Infertility: Diagnostic Perspectives.Biomolecules · 2025Review
- Molecular Characterization ofInfectious disease reports · 2025Article
- Lower Semen Quality Among Men in the Modern Era-Is There a Role for Diet and the Microbiome?Microorganisms · 2025Review
- Mechanisms by which phytogenic extracts enhance livestock reproductive health: current insights and future directions.Frontiers in veterinary science · 2025Review
- An overview regarding the relationship between Mollicutes, infertility and antibiotic resistance (Review).Biomedical reports · 2024Review
- Antimicrobial resistance of genital mycoplasmas recovered from nonpregnant women in Greece: trends over the last 15 years.Future microbiology · 2024Article
- Prevalence ofHealthcare (Basel, Switzerland) · 2023Article
- Are sexually transmitted infections associated with male infertility? A systematic review and in-depth evaluation of the evidence and mechanisms of action of 11 pathogens.Arab journal of urology · 2023Review
- Characteristics of common pathogens of urogenital tract among outpatients in Shanghai, China from 2016 to 2021.Frontiers in public health · 2023Article
- Association between serumFrontiers in public health · 2023Article
- Identification of sacrococcygeal and pelvic abscesses infected with invasive Mycoplasma hominis by MALDI-TOF MS.Journal of clinical laboratory analysis · 2022Article
- Development of a RPA-CRISPR-Cas12a Assay for Rapid, Simple, and Sensitive Detection ofFrontiers in microbiology · 2022Article
- Monitoring Sexually Transmitted Infections in Cervicovaginal Exfoliative Samples in Mexican Women.Pathogens (Basel, Switzerland) · 2021Article
- Association of Chlamydia Trachomatis Sero-Positivity with Male Infertility in the Niger-Delta Region of Nigeria: A Case-Control Study.Journal of the West African College of SurgeonsArticle
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6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Female and male infertility have been associated to Chlamydia trachomatis, Ureaplasma spp. and Mycoplasma hominis urogenital infections. However, evidence from large studies assessing their prevalence and putative associations in patients with infertility is still scarce. The study design was a cross-sectional study including 5464 patients with a recent diagnosis of couple's primary infertility and 404 healthy control individuals from Cordoba, Argentina. Overall, the prevalence of C. trachomatis, Ureaplasma spp. and M. hominis urogenital infection was significantly higher in patients than in control individuals (5.3%, 22.8% and 7.4% vs. 2.0%, 17.8% and 1.7%, respectively). C. trachomatis and M. hominis infections were significantly more prevalent in male patients whereas Ureaplasma spp. and M. hominis infections were more prevalent in female patients. Of clinical importance, C. trachomatis and Ureaplasma spp. infections were significantly higher in patients younger than 25 years. Moreover, Ureaplasma spp. and M. hominis infections were associated to each other in either female or male patients being reciprocal risk factors of their co-infection. Our data revealed that C. trachomatis, Ureaplasma spp. and M. hominis are prevalent uropathogens in patients with couple's primary infertility. These results highlight the importance of including the screening of urogenital infections in the diagnostic workup of infertility.
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