Evidence map›Paper›PMID 34211040›Full record

ArticleScientific reports2021

Determination of k-mer density in a DNA sequence and subsequent cluster formation algorithm based on the application of electronic filter.

Bimal Kumar Sarkar, Ashish Ranjan Sharma, Manojit Bhattacharya, Garima Sharma, Sang-Soo Lee, Chiranjib Chakraborty

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. A survey of k-mer methods and applications in bioinformatics.Computational and structural biotechnology journal · 2024
    Review
  3. Review
  4. Alignment-free sequence comparison for virus genomes based on location correlation coefficient.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Bimal Kumar Sarkar *Department of Physics, Adamas University, Kolkata, 700126, India.
Ashish Ranjan Sharma *Institute for Skeletal Aging and Orthopedic Surgery, Chuncheon Sacred Heart Hospital, Hallym University, College of Medicine, Chuncheon-si, Gangwon-do, 24252, Republic of Korea.
Manojit BhattacharyaDepartment of Zoology, Fakir Mohan University, Vyasa Vihar, Balasore, Odisha, 756020, India.
Garima SharmaNeuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chuncheon-si, Gangwon-do, Republic of Korea.
Sang-Soo LeeInstitute for Skeletal Aging and Orthopedic Surgery, Chuncheon Sacred Heart Hospital, Hallym University, College of Medicine, Chuncheon-si, Gangwon-do, 24252, Republic of Korea. 123sslee@gmail.com.
Chiranjib ChakrabortyDepartment of Biotechnology, School of Life Science and Biotechnology, Adamas University, Barasat-Barrackpore, Rd, Jagannathpur, Kolkata, West Bengal, 700126, India. drchiranjib@yahoo.com.
Adamas University · INFakir Mohan University · INHallym University · KRHallym University Chuncheon Sacred Heart Hospital · KRKangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a novel algorithm for information recovery from DNA sequences by using a digital filter. This work proposes a three-part algorithm to decide the k-mer or q-gram word density. Employing a finite impulse response digital filter, one can calculate the sequence's k-mer or q-gram word density. Further principal component analysis is used on word density distribution to analyze the dissimilarity between sequences. A dissimilarity matrix is thus formed and shows the appearance of cluster formation. This cluster formation is constructed based on the alignment-free sequence method. Furthermore, the clusters are used to build phylogenetic relations. The cluster algorithm is in good agreement with alignment-based algorithms. The present algorithm is simple and requires less time for computation than other currently available algorithms. We tested the algorithm using beta hemoglobin coding sequences (HBB) of 10 different species and 18 primate mitochondria genome (mtDNA) sequences.

Indexed as

AlgorithmsAnimalsBase Sequencebeta-GlobinsCluster AnalysisDNADNA, MitochondrialGenome, MitochondrialHumansPhylogenyPrincipal Component AnalysisSequence Analysis, DNAbeta-GlobinsDNADNA, Mitochondrial

Identifiers

PMID34211040
PMCPMC8249421
OpenAlexW3176543115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.