Evidence map›Paper›PMID 34210964›Full record

ArticleNPJ aging and mechanisms of disease2021

Two separate, large cohorts reveal potential modifiers of age-associated variation in visual reaction time performance.

J S Talboom, M D De Both, M A Naymik, A M Schmidt, C R Lewis, W M Jepsen, A K Håberg, T Rundek, B E Levin, S Hoscheidt and 8 more

Abstract read
In one paragraph

Article in NPJ aging and mechanisms of disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  19. Nonlinear Dynamics of Reaction Time and Time Estimation during Repetitive Test.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

J S TalboomThe Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.ORCID http://orcid.org/0000-0002-4327-4103
M D De BothThe Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.
M A NaymikThe Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.
A M SchmidtThe Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.
C R LewisThe Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.
W M JepsenThe Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.
A K HåbergNorwegian University of Science and Technology, Trondheim, Norway.
T RundekUniversity of Miami Miller School of Medicine and Evelyn F. McKnight Brain Institute, Miami, FL, USA.ORCID http://orcid.org/0000-0002-7115-9815
B E LevinUniversity of Miami Miller School of Medicine and Evelyn F. McKnight Brain Institute, Miami, FL, USA.
S HoscheidtArizona Alzheimer's Consortium, Phoenix, AZ, USA.
Y BollaArizona Alzheimer's Consortium, Phoenix, AZ, USA.
R D BrintonArizona Alzheimer's Consortium, Phoenix, AZ, USA.
N J SchorkThe Translational Genomics Research Institute (TGen), Phoenix, AZ, USA.
M HayArizona Alzheimer's Consortium, Phoenix, AZ, USA.
C A BarnesArizona Alzheimer's Consortium, Phoenix, AZ, USA.
E GliskyArizona Alzheimer's Consortium, Phoenix, AZ, USA.
L RyanArizona Alzheimer's Consortium, Phoenix, AZ, USA.
M J HuentelmanThe Translational Genomics Research Institute (TGen), Phoenix, AZ, USA. mhuentelman@tgen.org.ORCID http://orcid.org/0000-0001-7390-9918

Funding

Systems BiologyU19AG023122 · NIA · TRANSLATIONAL GENOMICS RESEARCH INST · PI JODI A LAPIDUS · 2004 to 2026
$102.6M
Integrative Resource to Develop Translational Strategies to Promote LongevityU24AG051129 · NIA · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI CUMMINGS, STEVEN RON, EVANS, DANIEL SPENCER · 2015 to 2019
$5.3M
Neural System Dynamics & Gene Expression Supporting Successful Cognitive AgingR01AG049465 · NIA · UNIVERSITY OF ARIZONA · PI BARNES, CAROL A. · 2014 to 2018
$3.6M
Integrative Omics to enhance therapeutics development for healthy agingUH2AG064706 · NIA · TRANSLATIONAL GENOMICS RESEARCH INST · PI MILLER, RICHARD A, SCHORK, NICHOLAS JOSEPH · 2019 to 2020
$1.4M
Medical Research Council MC_PC_17228Medical Research Council MC_QA137853NIA NIH HHS R01 AG049465NIA NIH HHS U19 AG023122NIA NIH HHS U24 AG051129NIA NIH HHS UH2 AG064706
6 · The paper itself

Abstract

To identify potential factors influencing age-related cognitive decline and disease, we created MindCrowd. MindCrowd is a cross-sectional web-based assessment of simple visual (sv) reaction time (RT) and paired-associate learning (PAL). svRT and PAL results were combined with 22 survey questions. Analysis of svRT revealed education and stroke as potential modifiers of changes in processing speed and memory from younger to older ages (n

Identifiers

PMID34210964
PMCPMC8249619

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.