Evidence map›Paper›PMID 34210784›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

The Gliopeptide ODN, a Ligand for the Benzodiazepine Site of GABA

Rhita Lamtahri, Mahmoud Hazime, Emma K Gowing, Raghavendra Y Nagaraja, Julie Maucotel, Michael Alasoadura, Pascale P Quilichini, Katia Lehongre, Benjamin Lefranc, Katarzyna Gach-Janczak and 6 more

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Brain Oscillatory Modes as a Proxy of Stroke Recovery.Neurorehabilitation and neural repair · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. The Excessive Tonic Inhibition of the Peri-infarct Cortex Depresses Low Gamma Rhythm Power During Poststroke Recovery.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Rhita LamtahriNormandie Université, UNIROUEN, Institut National de la Santé et de la Recherche Médicale U1239, Neuronal and Neuroendocrine Differentiation and Communication, Rouen, France.
Mahmoud HazimeNormandie Université, UNIROUEN, Institut National de la Santé et de la Recherche Médicale U1239, Neuronal and Neuroendocrine Differentiation and Communication, Rouen, France.
Emma K GowingDepartment of Anatomy, Brain Health Research Centre and Brain Research New Zealand, University of Otago, Dunedin, 76000, 9054, New Zealand.
Raghavendra Y NagarajaDepartment of Anatomy, Brain Health Research Centre and Brain Research New Zealand, University of Otago, Dunedin, 76000, 9054, New Zealand.
Julie MaucotelNormandie Université, UNIROUEN, Animal Facility, Rouen, 76000, France.
Michael AlasoaduraNormandie Université, UNIROUEN, Institut National de la Santé et de la Recherche Médicale U1239, Neuronal and Neuroendocrine Differentiation and Communication, Rouen, France.
Pascale P QuilichiniAix Marseille Univ, INSERM, INS, Inst Neurosci Syst, 13005, Marseille, France.ORCID https://orcid.org/0000-0001-9081-8655
Katia LehongreInserm U 1127, Centre National de la Recherche Scientifique Unite Mixte de Recherche 7225, Sorbonne Universités, UPMC Univ Paris 06 Unite Mixte de Recherche S 1127, Institut du Cerveau et de la Moelle épinière, ICM, Paris, F-75013, France.
Benjamin LefrancNormandie Université, UNIROUEN, Institut National de la Santé et de la Recherche Médicale U1239, Neuronal and Neuroendocrine Differentiation and Communication, Rouen, France.
Katarzyna Gach-JanczakNormandie Université, UNIROUEN, Institut National de la Santé et de la Recherche Médicale U1239, Neuronal and Neuroendocrine Differentiation and Communication, Rouen, France.
Ann-Britt MarcherDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, 5230, Denmark.
Susanne MandrupDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, 5230, Denmark.
David VaudryNormandie Université, UNIROUEN, Institut National de la Santé et de la Recherche Médicale U1239, Neuronal and Neuroendocrine Differentiation and Communication, Rouen, France.
Andrew N ClarksonDepartment of Anatomy, Brain Health Research Centre and Brain Research New Zealand, University of Otago, Dunedin, 76000, 9054, New Zealand.
Jérôme LeprinceNormandie Université, UNIROUEN, Institut National de la Santé et de la Recherche Médicale U1239, Neuronal and Neuroendocrine Differentiation and Communication, Rouen, France.
Julien ChuquetNormandie Université, UNIROUEN, Institut National de la Santé et de la Recherche Médicale U1239, Neuronal and Neuroendocrine Differentiation and Communication, Rouen, France julien.chuquet@univ-rouen.fr.ORCID https://orcid.org/0000-0002-0972-6874

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following stroke, the survival of neurons and their ability to reestablish connections is critical to functional recovery. This is strongly influenced by the balance between neuronal excitation and inhibition. In the acute phase of experimental stroke, lethal hyperexcitability can be attenuated by positive allosteric modulation of GABA

Indexed as

AdultAnimalsAstrocytesCortical Spreading DepressionDiazepam Binding InhibitorDrug ImplantsEvoked Potentials, SomatosensoryFemaleGABA-A Receptor AgonistsHumansHydrogelsInfarction, Middle Cerebral ArteryIntracranial ThrombosisLightMiceMice, Inbred C57BLDiazepam Binding Inhibitordiazepam binding inhibitor (33-50)Drug ImplantsGABA-A Receptor AgonistsHydrogelsNeuropeptidesN-MethylaspartatePeptide FragmentsReceptors, GABA-ARose Bengalendozepineinhibitionpeptideperi-infarctrecoverystroke

Identifiers

PMID34210784
PMCPMC8372017

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.