ArticleAnimal microbiome2021
Metagenomics analysis revealed the distinctive ruminal microbiome and resistive profiles in dairy buffaloes.
Article in Animal microbiome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 25 citations in OpenAlex.
- Genomic Insights Into the Probiotic and Safety Attributes of Pediococcus acidilactici BC-7 for its Potential Application in Livestock Health.Probiotics and antimicrobial proteins · 2026Article
- Lactiplantibacillus plantarum and Pediococcus acidilactici strains isolated from cattle gut show probiotic potential.BMC microbiology · 2026Article
- Traditional Fermented Dairy Products as Reservoirs of Bifidobacterium With Probiotic Potential: From Microbial Diversity to Functional Characterization.Comprehensive reviews in food science and food safety · 2026Review
- The resistome bridge between livestock and workers: novel frameworks for early detection and monitoring of antimicrobial resistance.Frontiers in public health · 2026Review
- Study on the Plateau Adaptive Synergistic Mechanism of Rumen Microbiome-Metabolome-Resistome in Tibetan Sheep.Microorganisms · 2025Article
- Rumen Microbiota in Cattle and Buffaloes: Insights into Host-Specific Bacterial Diversity.Biology · 2025Article
- Integrating the milk microbiome signatures in mastitis: milk-omics and functional implications.World journal of microbiology & biotechnology · 2025Review
- The Contribution of Dairy Bedding and Silage to the Dissemination of Genes Coding for Antimicrobial Resistance: A Narrative Review.Antibiotics (Basel, Switzerland) · 2024Review
- Metagenomics Analysis Reveals the Composition and Functional Differences of Fecal Microbiota in Wild, Farm, and Released Chinese Three-Keeled Pond Turtles (Animals : an open access journal from MDPI · 2024Article
- Comparison of average daily gain, apparent digestibility, rumen fermentation parameters and bacterial communities, and serum antioxidant indices in Leizhou goats fed with or without rumen-protected fat.Frontiers in veterinary science · 2024Article
- Relationships among bacterial cell size, diversity, and taxonomy in rumen.Frontiers in microbiology · 2024Article
- Comparative Rumen Metagenome and CAZyme Profiles in Cattle and Buffaloes: Implications for Methane Yield and Rumen Fermentation on a Common Diet.Microorganisms · 2023Article
- Exploring the rumen microbiota of Hu lambs in response to diet with paper mulberry.Applied microbiology and biotechnology · 2023Article
- Citrus flavonoid extracts alter the profiling of rumen antibiotic resistance genes and virulence factors of dairy cows.Frontiers in microbiology · 2023Article
- Comparative analysis of rumen metagenome, metatranscriptome, fermentation and methane yield in cattle and buffaloes fed on the same diet.Frontiers in microbiology · 2023Article
- An Age Effect of Rumen Microbiome in Dairy Buffaloes Revealed by Metagenomics.Microorganisms · 2022Article
- Opportunities and challenges of using metagenomic data to bring uncultured microbes into cultivation.Microbiome · 2022Article
- De-oiled palm kernel cake for stall-fed buffaloes: effect on milk constituents, nutrient digestibility, biochemical parameters, and rumen fermentation.Tropical animal health and production · 2022Article
- Comparative Analyses of Antibiotic Resistance Genes in Jejunum Microbiota of Pigs in Different Areas.Frontiers in cellular and infection microbiology · 2022Article
- Characterisation of the rumen resistome in Spanish dairy cattle.Animal microbiome · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundAntimicrobial resistance poses super challenges in both human health and livestock production. Rumen microbiota is a large reservoir of antibiotic resistance genes (ARGs), which show significant varations in different host species and lifestyles. To compare the microbiome and resistome between dairy cows and dairy buffaloes, the microbial composition, functions and harbored ARGs of rumen microbiota were explored between 16 dairy cows (3.93 ± 1.34 years old) and 15 dairy buffaloes (4.80 ± 3.49 years old) using metagenomics.
resultsDairy buffaloes showed significantly different bacterial species (LDA > 3.5 & P < 0.01), enriched KEGG pathways and CAZymes encoded genes (FDR < 0.01 & Fold Change > 2) in the rumen compared with dairy cows. Distinct resistive profiles were identified between dairy cows and dairy buffaloes. Among the total 505 ARGs discovered in the resistome of dairy cows and dairy buffaloes, 18 ARGs conferring resistance to 16 antibiotic classes were uniquely detected in dairy buffaloes. Gene tcmA (resistance to tetracenomycin C) presented high prevalence and age effect in dairy buffaloes, and was also highly positively correlated with 93 co-expressed ARGs in the rumen (R = 0.98 & P = 5E-11). In addition, 44 bacterial species under Lactobacillus genus were found to be associated with tcmA (R > 0.95 & P < 0.001). L. amylovorus and L. acidophilus showed greatest potential of harboring tcmA based on co-occurrence analysis and tcmA-containing contigs taxonomic alignment.
conclusionsThe current study revealed distinctive microbiome and unique ARGs in dairy buffaloes compared to dairy cattle. Our results provide novel understanding on the microbiome and resistome of dairy buffaloes, the unique ARGs and associated bacteria will help develop strategies to prevent the transmission of ARGs.
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