Evidence map›Paper›PMID 34210233›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2021

Anti-tubercular activity and molecular docking studies of indolizine derivatives targeting mycobacterial InhA enzyme.

Katharigatta N Venugopala, Sandeep Chandrashekharappa, Pran Kishore Deb, Christophe Tratrat, Melendhran Pillay, Deepak Chopra, Nizar A Al-Shar'i, Wafa Hourani, Lina A Dahabiyeh, Pobitra Borah and 12 more

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 13 institutions in 5 countries.

Katharigatta N VenugopalaDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.ORCID https://orcid.org/0000-0003-0680-1549
Sandeep ChandrashekharappaInstitute for Stem Cell Science and Regenerative Medicine (inStem), Bangalore, India.
Pran Kishore DebFaculty of Pharmacy, Department of Pharmaceutical Sciences, Philadelphia University, Amman, Jordan.ORCID https://orcid.org/0000-0002-8650-2874
Christophe TratratDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.
Melendhran PillayDepartment of Microbiology, National Health Laboratory Services, KZN Academic Complex, Inkosi Albert Luthuli Central Hospital, Durban, South Africa.
Deepak ChopraDepartment of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, India.
Nizar A Al-Shar'iFaculty of Pharmacy, Department of Medicinal Chemistry and Pharmacognosy, Jordan University of Science and Technology, Irbid, Jordan.ORCID https://orcid.org/0000-0002-1599-5704
Wafa HouraniFaculty of Pharmacy, Department of Pharmaceutical Sciences, Philadelphia University, Amman, Jordan.
Lina A DahabiyehDepartment of Pharmaceutical Sciences, School of Pharmacy, The University of Jordan, Amman, Jordan.ORCID https://orcid.org/0000-0002-4688-7052
Pobitra BorahPratiksha Institute of Pharmaceutical Sciences, Guwahati, India.
Rahul D NagdeveDepartment of Chemistry, Visvesvaraya National Institute of Technology, Nagpur, India.
Susanta K NayakDepartment of Chemistry, Visvesvaraya National Institute of Technology, Nagpur, India.
Basavaraj PadmashaliDepartment of Chemistry, School of Basic Science, Rani Channamma University, Belagavi, India.
Mohamed A MorsyDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.
Bandar E AldhubiabDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.ORCID https://orcid.org/0000-0002-2684-4186
Mahesh AttimaradDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.
Anroop B NairDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.ORCID https://orcid.org/0000-0003-2850-8669
Nagaraja SreeharshaDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.
Michelyne HarounDepartment of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.
Sheena ShashikanthDepartment of Studies in Organic Chemistry, University of Mysore, Mysore, India.
Viresh MohanlallDepartment of Biotechnology and Food Technology, Durban University of Technology, Durban, South Africa.
Raghuprasad MailavaramPharmaceutical Chemistry Division, Sri Vishnu College of Pharmacy, Bhimavaram, India.ORCID https://orcid.org/0000-0001-6126-5860
King Faisal University · SADurban University of Technology · ZAPhiladelphia University · JOVisvesvaraya National Institute of Technology · INHindu College of Pharmacy · INIndian Institute of Science Education and Research, Bhopal · INInstitute for Stem Cell Biology and Regenerative Medicine · INJordan University of Science and Technology · JONational Health Laboratory Service · ZANational Institute of Pharmaceutical Education and Research · INRani Channamma University, Belagavi · INUniversity of Jordan · JOUniversity of Mysore · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of 1,2,3-trisubstituted indolizines (

Indexed as

Antitubercular AgentsBacterial ProteinsIndolizinesMicrobial Sensitivity TestsMolecular Docking SimulationMycobacterium tuberculosisOxidoreductasesAntitubercular AgentsBacterial ProteinsIndolizinesInhA protein, MycobacteriumOxidoreductasesdockingIndolizineInhAmycobacterium tuberculosisX-ray crystal structure

Identifiers

PMID34210233
PMCPMC8259857
OpenAlexW3176146614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.