Evidence map›Paper›PMID 34210173›Full record

ReviewAntioxidants & redox signaling2021

Divergent Sepsis Pathophysiology in Older Adults.

Meagan S Kingren, Marlene E Starr, Hiroshi Saito

Abstract readReview
In one paragraph

Review in Antioxidants & redox signaling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Multi‑omics reveal neutrophil heterogeneity in sepsis (Review).International journal of molecular medicine · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Article
  18. Article
  19. Research Progress of DcR3 in the Diagnosis and Treatment of Sepsis.International journal of molecular sciences · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Meagan S KingrenAging and Critical Care Research Laboratory, Departments of University of Kentucky, Lexington, Kentucky, USA.
Marlene E StarrAging and Critical Care Research Laboratory, Departments of University of Kentucky, Lexington, Kentucky, USA.
Hiroshi SaitoAging and Critical Care Research Laboratory, Departments of University of Kentucky, Lexington, Kentucky, USA.ORCID 0000-0002-5845-5177

Funding

Visceral fat gamma delta T cells in sepsis pathogenesisR01GM129532 · NIGMS · UNIVERSITY OF KENTUCKY · PI STARR, MARLENE ELENA · 2018 to 2022
$1.6M
Mechanisms mediating severity of acute pancreatitis in the agedR01AG055359 · NIA · UNIVERSITY OF KENTUCKY · PI SAITO, HIROSHI · 2017 to 2021
$1.6M
The Role of Adipose Tissue in Age-dependent Sensitivity to Critical IllnessR01AG039732 · NIA · UNIVERSITY OF KENTUCKY · PI SAITO, HIROSHI · 2011 to 2015
$1.5M
Chronic muscle weakness in sepsis survivorsR01GM126181 · NIGMS · UNIVERSITY OF KENTUCKY · PI SAITO, HIROSHI · 2017 to 2020
$1.2M
NIA NIH HHS R01 AG039732NIA NIH HHS R01 AG055359NIGMS NIH HHS R01 GM126181NIGMS NIH HHS R01 GM129532
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultHumansSepsisagingcomorbidityinflammationoxidative stresssepsisthrombosis

Identifiers

PMID34210173
PMCPMC8905233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.