Evidence map›Paper›PMID 34210156›Full record

ArticleJournal of the American Heart Association2021

Association of Socioeconomic Disadvantage With Mortality and Readmissions Among Older Adults Hospitalized for Pulmonary Embolism in the United States.

Rishi K Wadhera, Eric A Secemsky, Yun Wang, Robert W Yeh, Samuel Z Goldhaber

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Household Income Differences and Variations in Management and Outcomes of Patients With Acute Pulmonary Embolism.Journal of the Society for Cardiovascular Angiography & Interventions · 2026
    Article
  3. Observational
  4. Review
  5. Impact of Social Determinants of Health on Cardiovascular Disease.Journal of the American Heart Association · 2025
    Review
  6. Article
  7. Temporal trend in venous thromboembolism hospitalization rates in Brazil.Revista da Associacao Medica Brasileira (1992) · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Observational
  13. Racial and gender disparities in the management of acute pulmonary embolism.Journal of vascular surgery. Venous and lymphatic disorders · 2024
    Article
  14. Unchanging Mortality from Pulmonary Embolism in the United States.Annals of the American Thoracic Society · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Home Treatment of Patients with Pulmonary Embolism: A Single Center 10-Year Experience from Ljubljana Registry.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rishi K WadheraRichard and Susan Smith Center for Outcomes Research in Cardiology Division of Cardiology Beth Israel Deaconess Medical and Harvard Medical School Boston MA.
Eric A SecemskyRichard and Susan Smith Center for Outcomes Research in Cardiology Division of Cardiology Beth Israel Deaconess Medical and Harvard Medical School Boston MA.
Yun WangRichard and Susan Smith Center for Outcomes Research in Cardiology Division of Cardiology Beth Israel Deaconess Medical and Harvard Medical School Boston MA.
Robert W YehRichard and Susan Smith Center for Outcomes Research in Cardiology Division of Cardiology Beth Israel Deaconess Medical and Harvard Medical School Boston MA.
Samuel Z GoldhaberDivision of Cardiovascular Medicine Brigham and Women's Hospital Harvard Medical School Boston MA.
Harvard University · USBrigham and Women's Hospital · US

Funding

Use of Registries, Claims and Health System Data to Enhance the Evaluation of Cardiovascular Therapies in Clinical TrialsR01HL136708 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Issa J. Dahabreh, Robert Yeh · 2017 to 2026
$6.9M
Explaining Rising Heart Failure Mortality in MedicareK23HL148525 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI WADHERA, RISHI KUMAR · 2019 to 2023
$863k
Shared Decision-Making to Improve the Health Status of Patients with Claudication: Developing and Implementing Strategies to Individualize Treatment DecisionsK23HL150290 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SECEMSKY, ERIC ALEXANDER · 2020 to 2024
$851k
NHLBI NIH HHS K23 HL148525NHLBI NIH HHS K23 HL150290NHLBI NIH HHS R01 HL136708
6 · The paper itself

Abstract

Background In the United States, hospitalizations for pulmonary embolism (PE) are increasing among older adults insured by Medicare. Although efforts to reduce health disparities have intensified, it remains unclear whether clinical outcomes differ between socioeconomically disadvantaged and nondisadvantaged Medicare beneficiaries hospitalized with PE. Methods and Results In this study, there were 53 386 Medicare fee-for-service beneficiaries age ≥65 years hospitalized for PE between October 2015 and January 2017. Of these, 5494 (10.3%) were socioeconomically disadvantaged and 47 892 (89.7%) were nondisadvantaged. Socioeconomically disadvantaged adults were of similar age as nondisadvantaged adults (77.1 versus 77.0), more likely to be female (68.5% versus 54.2%), and less likely to receive advanced therapies (11.0% versus 12.1%). After adjustment for demographics, 90-day all-cause mortality rates were similar between disadvantaged and nondisadvantaged adults. In contrast, 1-year mortality rates were higher among socioeconomically disadvantaged adults (hazard ratio [HR], 1.16; 95% CI, 1.10-1.22), although these differences were partially attenuated after additional adjustments for comorbidities and PE severity (HR, 1.09; 95% CI, 1.02-1.16). Risk-adjusted 30-day and 90-day all-cause readmission rates were substantially higher among socioeconomically disadvantaged patients (30-day HR, 1.14 [95% CI, 1.06-1.22]; 90-day HR, 1.18 [95% CI, 1.12-1.25]). In addition, 90-day readmissions attributed to PE, deep vein thrombosis, and/or bleeding were higher among socioeconomically disadvantaged patients (HR, 1.16; 95% CI, 1.02-1.32). Conclusions Socioeconomically disadvantaged older adults hospitalized with PE have higher 1-year mortality rates compared with their nondisadvantaged counterparts. Nearly 1 in 3 socioeconomically disadvantaged older adults was readmitted within 90 days of a hospitalization for PE. Targeted strategies are needed to improve transitional and ambulatory care for this vulnerable population.

Indexed as

Healthcare DisparitiesPatient ReadmissionSocial ClassSocial Determinants of HealthAgedAged, 80 and overAge FactorsFemaleHumansMaleMedicarePrognosisPulmonary EmbolismRisk AssessmentRisk FactorsTime Factorshealthcare disparitiesmortalitypulmonary embolismreadmissionssocioeconomic disadvantage

Identifiers

PMID34210156
PMCPMC8403328
OpenAlexW3173419392

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.