Evidence map›Paper›PMID 34210108›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Micafungin-Induced Cell Wall Damage Stimulates Morphological Changes Consistent with Microcycle Conidiation in

Samantha Reese, Cynthia Chelius, Wayne Riekhof, Mark R Marten, Steven D Harris

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Effect of Shock Waves on the Growth ofJournal of fungi (Basel, Switzerland) · 2022
    Article
  8. Potential Antifungal Targets forInternational journal of molecular sciences · 2022
    Review
  9. Article
  10. The Antifungal Effects of Citral onJournal of fungi (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Samantha ReeseSchool of Biological Sciences, University of Nebraska, Lincoln, NE 68503, USA.ORCID 0000-0003-4865-2633
Cynthia CheliusBiologics Development, Global Product Development and Supply, Bristol Myers Squibb Company, Devens, MA 01434, USA.
Wayne RiekhofSchool of Biological Sciences, University of Nebraska, Lincoln, NE 68503, USA.
Mark R MartenDepartment of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD 21250, USA.
Steven D HarrisDepartment of Plant Pathology and Microbiology and Department of Entomology, Iowa State University, Ames, IA 50011, USA.
University of Nebraska–Lincoln · USBristol-Myers Squibb (United States) · USIowa State University · USUniversity of Maryland, Baltimore County · US

Funding

NASA 80NSSC17K0737National Science Foundation 2006189
6 · The paper itself

Abstract

Fungal cell wall receptors relay messages about the state of the cell wall to the nucleus through the Cell Wall Integrity Signaling (CWIS) pathway. The ultimate role of the CWIS pathway is to coordinate repair of cell wall damage and to restore normal hyphal growth. Echinocandins such as micafungin represent a class of antifungals that trigger cell wall damage by affecting synthesis of β-glucans. To obtain a better understanding of the dynamics of the CWIS response and its multiple effects, we have coupled dynamic transcriptome analysis with morphological studies of

Indexed as

Aspergillus nidulansBrlAcell wall integrity signaling pathwaymicafunginmicrocycle conidiationRNA-Sequencing

Identifiers

PMID34210108
PMCPMC8306900
OpenAlexW3174219818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.