Evidence map›Paper›PMID 34210104›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Oxidative Stress Causes Vacuolar Fragmentation in the Human Fungal Pathogen

Donghyeun Kim, Moonyong Song, Eunsoo Do, Yoojeong Choi, James W Kronstad, Won Hee Jung

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Treatment ofFrontiers in toxicology · 2026
    Article
  3. The Vacuolar Protein 8 (Vac8) Homolog inJournal of fungi (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Measuring Stress Phenotypes in Cryptococcus neoformans.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Donghyeun KimDepartment of Systems Biotechnology, Chung-Ang University, Anseong 17546, Korea.ORCID 0000-0003-4641-8448
Moonyong SongDepartment of Systems Biotechnology, Chung-Ang University, Anseong 17546, Korea.
Eunsoo DoDepartment of Microbiology, University of Georgia, Athens, GA 30602, USA.
Yoojeong ChoiDepartment of Systems Biotechnology, Chung-Ang University, Anseong 17546, Korea.
James W KronstadMichael Smith Laboratories, Department of Microbiology & Immunology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.ORCID 0000-0003-4240-6976
Won Hee JungDepartment of Systems Biotechnology, Chung-Ang University, Anseong 17546, Korea.ORCID 0000-0002-6920-0233
Chung-Ang University · KRUniversity of British Columbia · CAUniversity of Georgia · US

Funding

Comparative and functional genomics of C. neoformansR01AI053721 · NIAID · UNIVERSITY OF BRITISH COLUMBIA · PI KRONSTAD, JAMES W · 2003 to 2024
$5.4M
National Institute of Allergy and Infectious Diseases RO1 AI053721National Research Foundation of Korea 2019R1A4A1024764National Research Foundation of Korea 2019R1F1A1061930NIAID NIH HHS R01 AI053721
6 · The paper itself

Abstract

Vacuoles are dynamic cellular organelles, and their morphology is altered by various stimuli or stresses. Vacuoles play an important role in the physiology and virulence of many fungal pathogens. For example, a

Indexed as

Cryptococcus neoformansfragmentationoxidative stresssuperoxide dismutasevacuole

Identifiers

PMID34210104
PMCPMC8305764
OpenAlexW3173521856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.