Evidence map›Paper›PMID 34210073›Full record

ArticleViruses2021

Detection of Q129H Immune Escape Mutation in Apparently Healthy Hepatitis B Virus Carriers in Southwestern Nigeria.

Olufisayo Adeyemi Adesina, Olusola Anuoluwapo Akanbi, Oluyinka Oladele Opaleye, Margaret Oluwatoyin Japhet, Bo Wang, Adekemi Olubukunola Oluyege, Patrycja Klink, C-Thomas Bock

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Olufisayo Adeyemi AdesinaDepartment of Microbiology, Obafemi Awolowo University, Ile-Ife 220282, Nigeria.
Olusola Anuoluwapo AkanbiDivision of Viral Gastroenteritis and Hepatitis Pathogens and Enteroviruses, Department of Infectious Diseases, Robert Koch Institute, 13353 Berlin, Germany.ORCID 0000-0002-1107-035X
Oluyinka Oladele OpaleyeDepartment of Medical Microbiology and Parasitology, Ladoke Akintola University of Technology, Ogbomoso 230232, Nigeria.
Margaret Oluwatoyin JaphetDepartment of Microbiology, Obafemi Awolowo University, Ile-Ife 220282, Nigeria.
Bo WangDivision of Viral Gastroenteritis and Hepatitis Pathogens and Enteroviruses, Department of Infectious Diseases, Robert Koch Institute, 13353 Berlin, Germany.ORCID 0000-0002-8560-9071
Adekemi Olubukunola OluyegeDepartment of Microbiology, Ekiti State University, Ado-Ekiti 360213, Nigeria.
Patrycja KlinkDivision of Viral Gastroenteritis and Hepatitis Pathogens and Enteroviruses, Department of Infectious Diseases, Robert Koch Institute, 13353 Berlin, Germany.ORCID 0000-0001-6139-9199
C-Thomas BockDivision of Viral Gastroenteritis and Hepatitis Pathogens and Enteroviruses, Department of Infectious Diseases, Robert Koch Institute, 13353 Berlin, Germany.ORCID 0000-0002-2773-486X
Robert Koch Institute · DEEkiti State University · NGLadoke Akintola University of Technology · NGObafemi Awolowo University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the global effort to eradicate hepatitis B continues, immune escape mutations (IEMs) and drug resistance mutations (DRMs) affecting its diagnosis, treatment, and prevention are compromising this goal. However, knowledge about the prevalence and circulation of these mutations in Nigeria is scarce. Serum samples (

Indexed as

MutationAdolescentAdultChildDNA, ViralFemaleGene Products, polGenotypeHepatitis BHepatitis B Surface AntigensHepatitis B virusHumansImmune EvasionMaleMiddle AgedNigeriaDNA, ViralGene Products, polHepatitis B Surface AntigensP protein, Hepatitis B virushepatitismutationNigeriaPCRphylogenyresistance

Identifiers

PMID34210073
PMCPMC8310067
OpenAlexW3173833735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.