ReviewBiomedicines2021
Near-Infrared-Triggered Upconverting Nanoparticles for Biomedicine Applications.
Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- X-optogenetic inhibition of VTA GABA neurons for wireless deep-brain stimulation and suppression of scratching behavior in freely moving mice.Materials today. Bio · 2026Article
- A chitosan/rGO/FeRSC advances · 2026Article
- Near-Infrared-Light-Driven Photochemistry and Photocatalysis: Mechanisms, Recent Applications, and Opportunities in Organic Synthesis and Biology.Angewandte Chemie (International ed. in English) · 2026Review
- Recent advances in enhancing the luminescence efficiency of rare earth upconversion nanoparticles for biomedical applications.RSC advances · 2026Review
- A near-infrared-controlled and logic gate sensing platform for the sensitive and specific detection of dual miRNAs.RSC advances · 2026Article
- Advances in nanotechnology for early cancer diagnosis: emerging nanoplatforms and multimodal imaging approaches.American journal of cancer research · 2026Review
- Recent Trends in Upconversion Luminescent Inorganic Materials and Nanomaterials for Enhanced Photovoltaic Solar Cell and Biological Applications.Journal of fluorescence · 2025Review
- Intersection of ferroptosis and nanomaterials brings benefits to breast cancer.Cell biology and toxicology · 2025Review
- Biophotonic (nano)structures: from fundamentals to emerging applications.RSC advances · 2025Review
- NIR-Induced Photoswitching Hybrid DNA Nanoconstruct-Based Drug Delivery System for Spatiotemporal Control of Stem Cell Fate.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Photothermal applications of upconversion nanoparticles.RSC advances · 2025Review
- Advancements in tantalum based nanoparticles for integrated imaging and photothermal therapy in cancer management.RSC advances · 2024Review
- Real-Time Tracking of Vesicles in Living Cells Reveals That Tau-Hyperphosphorylation Suppresses Unidirectional Transport by Motor Proteins.Chemical & biomedical imaging · 2024Article
- Highly sensitive and accurate detection of cholesterol based on a single red upconversion biosensor.RSC advances · 2024Article
- Synthesis of Highly Luminescent Silica-Coated Upconversion Nanoparticles from Lanthanide Oxides or Nitrates Using Co-Precipitation and Sol-Gel Methods.Gels (Basel, Switzerland) · 2023Article
- Poly(glycerol monomethacrylate)-encapsulated upconverting nanoparticles prepared by miniemulsion polymerization: morphology, chemical stability, antifouling properties and toxicity evaluation.Nanoscale advances · 2023Article
- Emerging trends in the development of flexible optrode arrays for electrophysiology.APL bioengineering · 2023Review
- Aptamer-Based Point-of-Care Devices: Emerging Technologies and Integration of Computational Methods.Biosensors · 2023Review
- Sustainable Synthesis of Highly Biocompatible 2D Boron Nitride Nanosheets.Biomedicines · 2022Article
- Upconversion Nanomaterials in Bioimaging and Biosensor Applications and Their Biological Response.Nanomaterials (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Due to the unique properties of lanthanide-doped upconverting nanoparticles (UCNP) under near-infrared (NIR) light, the last decade has shown a sharp progress in their biomedicine applications. Advances in the techniques for polymer, dye, and bio-molecule conjugation on the surface of the nanoparticles has further expanded their dynamic opportunities for optogenetics, oncotherapy and bioimaging. In this account, considering the primary benefits such as the absence of photobleaching, photoblinking, and autofluorescence of UCNPs not only facilitate the construction of accurate, sensitive and multifunctional nanoprobes, but also improve therapeutic and diagnostic results. We introduce, with the basic knowledge of upconversion, unique properties of UCNPs and the mechanisms involved in photon upconversion and discuss how UCNPs can be implemented in biological practices. In this focused review, we categorize the applications of UCNP-based various strategies into the following domains: neuromodulation, immunotherapy, drug delivery, photodynamic and photothermal therapy, bioimaging and biosensing. Herein, we also discuss the current emerging bioapplications with cutting edge nano-/biointerfacing of UCNPs. Finally, this review provides concluding remarks on future opportunities and challenges on clinical translation of UCNPs-based nanotechnology research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.