ArticleCancers2021
Impact of Race and Socioeconomics Disparities on Survival in Young-Onset Colorectal Adenocarcinoma-A SEER Registry Analysis.
Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 18 citations in OpenAlex.
- Identifying clinical and lifestyle factor mediators of the association between socioeconomic status and colorectal cancer mortality.SSM - population health · 2026Article
- Distance to Care, Regional Context, and Survival in Early-Onset Colorectal Cancer.Journal of surgical oncology · 2026Article
- Artificial Intelligence-Guided Analysis of WNT Pathway Alterations: Associations with Genomic Burden and Survival Across African American and Non-Hispanic White Populations, Age Groups, and FOLFOX Treatment in Colorectal Cancer.International journal of molecular sciences · 2026Article
- Exploring the role of marital status on survival and stage at diagnosis in early-onset colorectal cancer by race/ethnicity.Scientific reports · 2026Article
- Survival differences after diagnosis of early-onset colorectal cancer by race and ethnicity and neighborhood-level socioeconomic status.Journal of colon and rectal cancer · 2026Article
- Neighborhood Disadvantage and Cardiovascular Mortality Among Colorectal Cancer Survivors.Cancers · 2025Article
- Early-Onset Colorectal Cancer: A Review of Current Insights and a Call for Action.Biomedicines · 2025Review
- Differences in the epidemiology and survival of patients with colorectal cancer between China and the United States: a large cross-sectional study.Updates in surgery · 2025Article
- Vulnerability in Colorectal Cancer: Adjusted Gross Income and Geography as Factors in Determining Overall Survival in Colorectal Cancer: A Single-Center Study Across a Broad Income Inequality in an American Context.Current oncology (Toronto, Ont.) · 2024Article
- Racial and Ethnic Variation in Survival in Early-Onset Colorectal Cancer.JAMA network open · 2024Article
- Geographic Disparities in Cancer Incidence in the US Population Aged 20 to 49 Years, 2016-2020.Preventing chronic disease · 2024Article
- Construction and validation of a nomogram for predicting overall survival of patients with stage III/IV early-onset colorectal cancer.Frontiers in oncology · 2024Article
- Early-Onset Colorectal Cancer Survival Differences and Potential Geographic Determinants Among Men and Women in Utah.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · 2022Article
- Midlife brain metastases in the United States: Is male at risk?Cancer medicine · 2022Article
- Disparities in Recommendations for Colorectal Cancer Screening Among Average-Risk Individuals: An Ecobiosocial Approach.Risk management and healthcare policy · 2022Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWe aimed to assess the impact of socio-economic determinants of health (SEDH) on survival disparities within and between the ethnic groups of young-onset (<50 years age) colorectal adenocarcinoma patients. PATIENTS AND
methodsSurveillance, epidemiology, and end results (SEER) registry was used to identify colorectal adenocarcinoma patients aged between 25-49 years from 2012 and 2016. Survival analysis was performed using the Kaplan-Meir method. Cox proportional hazards model was used to determine the hazard effect of SEDH. American community survey (ACS) data 2012-2016 were used to analyze the impact of high school education, immigration status, poverty, household income, employment, marital status, and insurance type.
resultsA total of 17,145 young-onset colorectal adenocarcinoma patients were studied. Hispanic (H) = 2874, Non-Hispanic American Indian/Alaskan Native (NHAIAN) = 164, Non-Hispanic Asian Pacific Islander (NHAPI) = 1676, Non-Hispanic black (NHB) = 2305, Non-Hispanic white (NHW) = 10,126. Overall cancer-specific survival was, at 5 years, 69 m. NHB (65.58 m) and NHAIAN (65.67 m) experienced worse survival compared with NHW (70.11 m), NHAPI (68.7), and H (68.31). High school education conferred improved cancer-specific survival significantly with NHAPI, NHB, and NHW but not with H and NHAIAN. Poverty lowered and high school education improved cancer-specific survival (CSS) in NHB, NHW, and NHAPI. Unemployment was associated with lowered CSS in H and NAPI. Lower income below the median negatively impacted survival among H, NHAPI NHB, and NHW. Recent immigration within the last 12 months lowered CSS survival in NHW. Commercial health insurance compared with government insurance conferred improved CSS in all groups.
conclusionsSurvival disparities were found among all races with young-onset colorectal adenocarcinoma. The pattern of SEDH influencing survival was unique to each race. Overall higher income levels, high school education, private insurance, and marital status appeared to be independent factors conferring favorable survival found on multivariate analysis.
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