Evidence map›Paper›PMID 34209834›Full record

ReviewLife (Basel, Switzerland)2021

Paediatric Idiopathic Intracranial Hypertension (IIH)-A Review.

Andrew Malem, Twishaa Sheth, Brinda Muthusamy

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Elevated systemic venous pressures as a possible pathology in prepubertal pediatric idiopathic intracranial hypertension.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Observational
  14. Novel Approaches to the Treatment of Idiopathic Intracranial Hypertension.Current neurology and neuroscience reports · 2024
    Review
  15. The diagnostic value of MRI findings in pediatric idiopathic intracranial hypertension: a case-control study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  16. Review
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andrew MalemPaediatric Ophthalmology, Department of Ophthalmology, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
Twishaa ShethPaediatric Ophthalmology, Department of Ophthalmology, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.ORCID 0000-0002-9228-3487
Brinda MuthusamyPaediatric Ophthalmology, Department of Ophthalmology, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
Cambridge University Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paediatric idiopathic intracranial hypertension (IIH), is a rare but important differential diagnosis in children presenting with papilloedema. It is characterised by raised intracranial pressure in the absence of an identifiable secondary structural or systemic cause and is, therefore, a diagnosis of exclusion. In the adult population, there is a strong predilection for the disease to occur in female patients who are obese. This association is also seen in paediatric patients with IIH but primarily in the post-pubertal cohort. In younger pre-pubertal children, this is not the case, possibly reflecting a different underlying disease aetiology and pathogenesis. Untreated IIH in children can cause significant morbidity from sight loss, chronic headaches, and the psychological effects of ongoing regular hospital monitoring, interventions, and medication. The ultimate goal in the management of paediatric IIH is to protect the optic nerve from papilloedema-induced optic neuropathy and thus preserve vision, whilst reducing the morbidity from other symptoms of IIH, in particular chronic headaches. In this review, we will outline the typical work-up and diagnostic process for paediatric patients with suspected IIH and how we manage these patients.

Indexed as

headacheoptical coherence tomographyoptic nervepaediatric idiopathic intracranial hypertensionpapilloedemapseudo tumour cerebtivision

Identifiers

PMID34209834
PMCPMC8307434
OpenAlexW3173249249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.