ArticleViruses2021
Comparison of Hepatitis E Virus Sequences from Humans and Swine, the Netherlands, 1998-2015.
Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Genetic Heterogeneity of Hepatitis E Virus (HEV) in Wild Boars in Italy.Animals : an open access journal from MDPI · 2026Article
- Genetic insights into hepatitis E virus through environmental surveillance in Europe.One health (Amsterdam, Netherlands) · 2026Review
- Hepatitis E virus in wild boar from Poland.Scientific reports · 2026Article
- Hepatitis E in Wildlife: Emerging Threats to Human Health.Veterinary sciences · 2026Review
- Distinct distribution of HEV-3 subtypes across humans, animals, and environmental waters in Sweden.Emerging microbes & infections · 2025Article
- Zoonotic hepatitis E virus spreads through environmental routes in pig herds - A phylodynamic analysis.PLoS pathogens · 2025Article
- Article
- Hepatitis E Virus RNA Detection in Liver and Muscle Tissues Sampled from Home Slaughtered Domestic Pigs in Central Italy.Food and environmental virology · 2024Article
- Utility of various genome lengths in diversity and evolution analyses of Hepatitis E virus.Virus research · 2024Article
- Article
- The molecular epidemiology of hepatitis E virus genotype 3 in Canada.Epidemiology and infection · 2024Article
- Molecular Characterization and Phylogenetic Analysis of Hepatitis E Virus (HEV) Strains from Pigs Farmed in Eight European Countries between 2020 and 2022.Transboundary and emerging diseases · 2023Article
- Molecular epidemiology and genotype-specific disease severity of hepatitis E virus infections in Germany, 2010-2019.Emerging microbes & infections · 2022Article
- Identification of Hepatitis E Virus Genotypes 3 and 7 in Israel: A Public Health Concern?Viruses · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pigs are suspected to be a major source of zoonotic hepatitis E virus (HEV) infection in industrialized countries, but the transmission route(s) from pigs to humans are ill-defined. Sequence comparison of HEV isolates from pigs with those from blood donors and patients in 372 samples collected in the Netherlands in 1998 and 1999 and between 2008 and 2015 showed that all sequences were genotype 3 except for six patients (with travel history). Subgenotype 3c (gt3c) was the most common subtype. While the proportion of gt3c increased significantly between 1998 and 2008, it remained constant between 2008 and 2015. Among the few circulating HEV subtypes, there was no difference observed between the human and the pig isolates. Hepatitis E viruses in humans are very likely to originate from pigs, but it is unclear why HEV gt3c has become the predominant subtype in the Netherlands.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.