Evidence map›Paper›PMID 34209676›Full record

ArticleNutrients2021

Alcohol Consumption and Risk of Rheumatoid Arthritis among Chinese Adults: A Prospective Study.

Hannah VanEvery, Wenhao Yang, Nancy Olsen, Le Bao, Bing Lu, Shouling Wu, Liufu Cui, Xiang Gao

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. Alcohol Consumption and Autoimmune Diseases.International journal of molecular sciences · 2025
    Review
  9. Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Hannah VanEveryDepartment of Nutritional Sciences, The Pennsylvania State University, State College, PA 16802, USA.ORCID 0000-0002-0778-0607
Wenhao YangDepartment of Rheumatology and Immunology, Kailuan General Hospital, Tangshan 063000, China.
Nancy OlsenDivision of Rheumatology, Department of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA 17033, USA.
Le BaoDepartment of Statistics, The Pennsylvania State University, State College, PA 16802, USA.
Bing LuDepartment of Medicine, Harvard Medical School, Boston, MA 02115, USA.
Shouling WuDepartment of Cardiology, Kailuan General Hospital, Tangshan 063000, China.
Liufu CuiDepartment of Rheumatology and Immunology, Kailuan General Hospital, Tangshan 063000, China.
Xiang GaoDepartment of Nutritional Sciences, The Pennsylvania State University, State College, PA 16802, USA.ORCID 0000-0003-2617-6509
Kailuan General Hospital · CNPennsylvania State University · USHarvard University · USPenn State Milton S. Hershey Medical Center · US

Funding

Dietary Quality, Body Adiposity, and Risk of Rheumatoid Arthritis in WomenR01AR071326 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI LU, BING, SOLOMON, DANIEL HAL · 2018 to 2021
$1.8M
NIAMS NIH HHS R01 AR071326Pennsylvania State University Start-up Grant
6 · The paper itself

Abstract

Alcohol consumption may be associated with the risk of rheumatoid arthritis (RA), but potential sex-related differences in this association have not been explored. Thus, we utilized 87,118 participants in the Kailuan Study, a prospective cohort initiated in 2006 to study the risk factors of cardiovascular disease in a Chinese population. We included those that did not have RA at baseline (2006), and performed cox proportional hazard modeling to calculate the hazard ratio (HR) and 95% confidence interval (95% CI) of RA according to the levels of alcohol consumption (never or past, light or moderate (<1 serving/day for women, <2 servings/day for men), and heavy (>1 serving/day for women, >2 servings/day for men), adjusting for age, sex, body mass index, and smoking. Diagnoses of RA were confirmed via medical record review by rheumatologists. From 2006 to 2018, we identified 87 incident RA cases. After adjusting for potential confounders, the HR of RA was 1.26 (95% CI: 0.62, 2.56) for participants with light or moderate alcohol consumption and 1.98 (95% CI: 0.93, 4.22) for participants with heavy alcohol consumption) versus non-drinkers. The HR of each 10 g increase in alcohol consumption was 1.11 (95% CI: 0.98, 1.26) (

Indexed as

Sex FactorsAdolescentAdultAgedAged, 80 and overAlcohol DrinkingArthritis, RheumatoidBody Mass IndexChinaFemaleHumansMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk Factorsalcoholcohortepidemiologyprospectiverheumatoid arthritis

Identifiers

PMID34209676
PMCPMC8308382
OpenAlexW3174612885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.