Evidence map›Paper›PMID 34209669›Full record

ArticleCancers2021

RASSF1A Suppression as a Potential Regulator of Mechano-Pathobiology Associated with Mammographic Density in BRCA Mutation Carriers.

Gina Reye, Xuan Huang, Kara L Britt, Christoph Meinert, Tony Blick, Yannan Xu, Konstantin I Momot, Thomas Lloyd, Jason J Northey, Erik W Thompson and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. RASSF1A and its epigenetic dysregulation in genitourinary cancer: a current update.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Gina ReyeSchool of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD 4006, Australia.
Xuan HuangSchool of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD 4006, Australia.
Kara L BrittPeter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
Christoph MeinertHerston Biofabrication Institute, Metro North Hospital and Health Service, Brisbane, QLD 4029, Australia.ORCID 0000-0002-7036-4067
Tony BlickSchool of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD 4006, Australia.
Yannan XuCentral Analytical Research Facility, Queensland University of Technology, Brisbane, QLD 4000, Australia.
Konstantin I MomotFaculty of Science, School of Chemistry and Physics, Queensland University of Technology, Brisbane, QLD 4000, Australia.ORCID 0000-0002-5695-153X
Thomas LloydDepartment of Radiology, The Princess Alexandra Hospital, Woollongabba, QLD 4102, Australia.
Jason J NortheyDepartment of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.ORCID 0000-0003-3115-2560
Erik W ThompsonSchool of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD 4006, Australia.ORCID 0000-0002-9723-4924
Honor J HugoSchool of Biomedical Sciences, Queensland University of Technology, Brisbane, QLD 4006, Australia.
Translational Research Institute · AUQueensland University of Technology · AUGriffith University · AUPeter MacCallum Cancer Centre · AUPrincess Alexandra Hospital · AUQueensland Health · AUUniversity of California, San Francisco · US

Funding

PA Research Foundation Research Innovation Award
6 · The paper itself

Abstract

High mammographic density (MD) increases breast cancer (BC) risk and creates a stiff tissue environment. BC risk is also increased in

Indexed as

BRCA1/2 mutationsbreast cancermammographic densityRASSF1Astiffness

Identifiers

PMID34209669
PMCPMC8269117
OpenAlexW3176620305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.