Evidence map›Paper›PMID 34209637›Full record

ArticlePharmaceutics2021

Targeted Radionuclide Therapy Using Auger Electron Emitters: The Quest for the Right Vector and the Right Radionuclide.

Malick Bio Idrissou, Alexandre Pichard, Bryan Tee, Tibor Kibedi, Sophie Poty, Jean-Pierre Pouget

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. MHC-I-Driven Antitumor Immunity Counterbalances Low Absorbed Doses of Radiopharmaceutical Therapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Immunological effects of radiopharmaceutical therapy.Frontiers in nuclear medicine · 2024
    Review
  8. Marshalling the Potential of Auger Electron Radiopharmaceutical Therapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Review
  9. Article
  10. Dosimetry in Radiopharmaceutical Therapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Malick Bio IdrissouInstitut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, 34298 Montpellier, France.
Alexandre PichardInstitut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, 34298 Montpellier, France.
Bryan TeeDepartment of Nuclear Physics, Research School of Physics, Australian National University, Canberra, ACT 2601, Australia.ORCID 0000-0003-3941-2830
Tibor KibediDepartment of Nuclear Physics, Research School of Physics, Australian National University, Canberra, ACT 2601, Australia.
Sophie PotyInstitut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, 34298 Montpellier, France.
Jean-Pierre PougetInstitut de Recherche en Cancérologie de Montpellier, Inserm U1194, Université de Montpellier, Institut Régional du Cancer de Montpellier, 34298 Montpellier, France.
Inserm · FRAustralian National University · AU

Funding

Cancéropôle Grand Sud Ouest 2021Fondation ARC pour la recherche sur le cancer 2020 PJA3French National Research Agency as part of the Investissements d'Avenir program (ANR-10-LABX-53-01)Ligue Nationale contre le Cancer 2021SIRIC Montpellier Cancer Grant INCa_Inserm_DGOS_ 12553
6 · The paper itself

Abstract

Auger electron emitters (AEEs) are attractive tools in targeted radionuclide therapy to specifically irradiate tumour cells while sparing healthy tissues. However, because of their short range, AEEs need to be brought close to sensitive targets, particularly nuclear DNA, and to a lower extent, cell membrane. Therefore, radioimmunoconjugates (RIC) have been developed for specific tumour cell targeting and transportation to the nucleus. Herein, we assessed, in A-431

Indexed as

Auger electronsNLS peptidenuclear localisation sequenceradionuclide therapyTAT peptide

Identifiers

PMID34209637
PMCPMC8309076
OpenAlexW3173415182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.