Evidence map›Paper›PMID 34209587›Full record

ArticleCancers2021

Germline

Evan M Braunstein, Hang Chen, Felicia Juarez, Fanghan Yang, Lindsay Tao, Igor Makhlin, Donna M Williams, Shruti Chaturvedi, Aparna Pallavajjala, Theodoros Karantanos and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Evan M BraunsteinDepartment of Medicine, Division of Haematology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Hang ChenDepartment of Medicine, Division of Haematology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Felicia JuarezDepartment of Medicine, Division of Haematology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Fanghan YangDepartment of Medicine, Division of Haematology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Lindsay TaoDepartment of Medicine, Division of Haematology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Igor MakhlinDepartment of Medicine, Division of Hematology & Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Donna M WilliamsDepartment of Medicine, Division of Haematology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Shruti ChaturvediDepartment of Medicine, Division of Haematology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Aparna PallavajjalaDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Theodoros KarantanosDepartment of Medical Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-6792-8298
Renan MartinMcKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Elizabeth WohlerMcKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0001-6189-9839
Nara SobreiraMcKusick-Nathans Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Christopher D GockeDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-9541-2192
Alison R MoliternoDepartment of Medicine, Division of Haematology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-8673-4317
Johns Hopkins University · USUniversity of Pennsylvania · US

Funding

Baylor-Johns Hopkins Center for Mendelian GeneticsU54HG006542 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI VALLE, DAVID · 2012 to 2015
$15.6M
ADAMTS13 and Late Neurologic Morbidity after Thrombotic Thrombocytopenic PurpuraK99HL150594 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CHATURVEDI, SHRUTI · 2020 to 2023
$907k
Investigation of ERBB2 and ERBB3 in hematopoiesis and predisposition to hematologic diseaseK08HL138142 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BRAUNSTEIN, EVAN M · 2018 to 2021
$690k
Leukemia and Lymphoma Society Quest for CuresNHGRI NIH HHS U54HG006542NHLBI NIH HHS K08HL138142NHLBI NIH HHS K99 HL150594
6 · The paper itself

Abstract

Familial cases of myeloproliferative neoplasms (MPN) are relatively common, yet few inherited risk factors have been identified. Exome sequencing of a kindred with a familial cancer syndrome characterized by both MPN and melanoma produced a germline variant in the

Indexed as

familial cancergermline predispositionmyeloproliferative neoplasms

Identifiers

PMID34209587
PMCPMC8268839
OpenAlexW3174704232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.