Evidence map›Paper›PMID 34209530›Full record

ArticleAnimals : an open access journal from MDPI2021

Proteomic Analysis of Liver from Finishing Beef Cattle Supplemented with a Rumen-Protected B-Vitamin Blend and Hydroxy Trace Minerals.

Mariana Mescouto Lopes, Thaís Ribeiro Brito, Josiane Fonseca Lage, Thaís Correia Costa, Marta Maria Dos Santos Fontes, Nick Vergara Lopes Serão, Tiago Antônio de Oliveira Mendes, Ricardo Andrade Reis, Renata Veroneze, Fabyano Fonseca E Silva and 1 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Mariana Mescouto LopesDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa 36570-000, Brazil.
Thaís Ribeiro BritoDepartment of Animal Science, São Paulo State University, Jaboticabal 14887-900, Brazil.ORCID 0000-0002-8279-8081
Josiane Fonseca LageTrouw Nutrition, Research and Development, Campinas 13080-650, Brazil.
Thaís Correia CostaDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa 36570-000, Brazil.ORCID 0000-0002-6911-4677
Marta Maria Dos Santos FontesDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa 36570-000, Brazil.ORCID 0000-0003-1580-2551
Nick Vergara Lopes SerãoDepartment of Animal Science, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0002-6758-208X
Tiago Antônio de Oliveira MendesDepartment of Biochemistry and Molecular Biology, Universidade Federal de Viçosa, Viçosa 36570-000, Brazil.
Ricardo Andrade ReisDepartment of Animal Science, São Paulo State University, Jaboticabal 14887-900, Brazil.
Renata VeronezeDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa 36570-000, Brazil.
Fabyano Fonseca E SilvaDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa 36570-000, Brazil.ORCID 0000-0001-9536-1113
Marcio de Souza DuarteDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa 36570-000, Brazil.ORCID 0000-0002-5795-6420
Universidade Federal de Viçosa · BRUniversidade Estadual Paulista (Unesp) · BRIowa State University · USTrouw Nutrition (Brazil) · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 31883/2018-4Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Instituto Nacional de Ciência e Tecnologia de Ciência Animal 465377/2014-9Trouw Nutrition 50437475214
6 · The paper itself

Abstract

Vitamin B and trace minerals are crucial molecular signals involved in many biological pathways; however, their bioavailability is compromised in high-producing ruminant animals. So far, studies have mainly focused on the effects of these micronutrients on animal performance, but their use in a rumen-protected form and their impact on liver metabolism in finishing beef cattle is poorly known. We used a shotgun proteomic approach combined with biological network analyses to assess the effects of a rumen-protected B-vitamin blend, as well as those of hydroxy trace minerals, on the hepatic proteome. A total of 20 non-castrated Nellore males with 353 ± 43 kg of initial body weight were randomly assigned to one of the following treatments: CTRL-inorganic trace minerals without supplementation of a protected vitamin B blend, or SUP-supplementation of hydroxy trace minerals and a protected vitamin B blend. All animals were fed the same amount of the experimental diet for 106 days, and liver biopsies were performed at the end of the experimental period. Supplemented animals showed 37 up-regulated proteins (

Indexed as

beef cattlehydroxyl trace mineralsliver metabolismproteomicsvitamin B

Identifiers

PMID34209530
PMCPMC8300412
OpenAlexW3176280263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.