ArticlePolymers2021
Applied Rheology as Tool for the Assessment of Chitosan Hydrogels for Regenerative Medicine.
Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Chitosan-Olive Oil Oleogels for Food Applications: Physicochemical and Functional Properties.Foods (Basel, Switzerland) · 2025Article
- Combined Effect of pH and Neutralizing Solution Molarity on the Rheological Properties of Chitosan Hydrogels for Biomedical Applications.Gels (Basel, Switzerland) · 2025Article
- Polymeric Nanohydrogel in Topical Drug Delivery System.International journal of nanomedicine · 2024Review
- Novel Environmentally Responsive Polyvinyl Polyamine Hydrogels Capable of Phase Transformation with Temperature for Applications in Reservoir Profile Control.Gels (Basel, Switzerland) · 2023Article
- Glucose-Responsive Microgel Comprising Conventional Insulin and Curcumin-Laden Nanoparticles: a Potential Combination for Diabetes Management.The AAPS journal · 2023Article
- Rheological Considerations of Pharmaceutical Formulations: Focus on Viscoelasticity.Gels (Basel, Switzerland) · 2023Review
- New Smart Bioactive and Biomimetic Chitosan-Based Hydrogels for Wounds Care Management.Pharmaceutics · 2023Article
- Type-A Gelatin-Based Hydrogel Infiltration and Degradation in Titanium Foams as a Potential Method for Localised Drug Delivery.Polymers · 2023Article
- Review
- Synthesis of pH-Sensitive Cross-Linked Basil Seed Gum/Acrylic Acid Hydrogels by Free Radical Copolymerization Technique for Sustained Delivery of Captopril.Gels (Basel, Switzerland) · 2022Article
- Evaluation of lyophilized royal jelly and garlic extract emulgels using a murine model infected with methicillin-resistant Staphylococcus aureus.AMB Express · 2022Article
- Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The regeneration of soft tissues that connect, support or surround other tissues is of great interest. In this sense, hydrogels have great potential as scaffolds for their regeneration. Among the different raw materials, chitosan stands out for being highly biocompatible, which, together with its biodegradability and structure, makes it a great alternative for the manufacture of hydrogels. Therefore, the aim of this work was to develop and characterize chitosan hydrogels. To this end, the most important parameters of their processing, i.e., agitation time, pH, gelation temperature and concentration of the biopolymer used were rheologically evaluated. The results show that the agitation time does not have a significant influence on hydrogels, whereas a change in pH (from 3.2 to 7) is a key factor for their formation. Furthermore, a low gelation temperature (4 °C) favors the formation of the hydrogel, showing better mechanical properties. Finally, there is a percentage of biopolymer saturation, from which the properties of the hydrogels are not further improved (1.5 wt.%). This work addresses the development of hydrogels with high thermal resistance, which allows their use as scaffolds without damaging their mechanical properties.
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Registered trials
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