Evidence map›Paper›PMID 34209326›Full record

ArticlePolymers2021

Antimicrobial Polymeric Composites with Embedded Nanotextured Magnesium Oxide.

Nemanja Aničić, Mario Kurtjak, Samo Jeverica, Danilo Suvorov, Marija Vukomanović

Abstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nemanja AničićAdvanced Materials Department, Jozef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia.
Mario KurtjakAdvanced Materials Department, Jozef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia.ORCID 0000-0002-2334-5920
Samo JevericaNational Laboratory of Health, Environment and Food, Prvomajska 1, 2000 Maribor, Slovenia.
Danilo SuvorovAdvanced Materials Department, Jozef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia.
Marija VukomanovićAdvanced Materials Department, Jozef Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia.ORCID 0000-0001-7034-0471

Funding

Javna Agencija za Raziskovalno Dejavnost RS J2-8169Javna Agencija za Raziskovalno Dejavnost RS P2-0091Javna Agencija za Raziskovalno Dejavnost RS PR-05560
6 · The paper itself

Abstract

Nanotextured magnesium oxide (MgO) can exhibit both antibacterial and tissue regeneration activity, which makes it very useful for implant protection. To successfully combine these two properties, MgO needs to be processed within an appropriate carrier system that can keep MgO surface available for interactions with cells, slow down the conversion of MgO to the less active hydroxide and control MgO solubility. Here we present new composites with nanotextured MgO microrods embedded in different biodegradable polymer matrixes: poly-lactide-co-glycolide (PLGA), poly-lactide (PLA) and polycaprolactone (PCL). Relative to their hydrophilicity, polarity and degradability, the matrices were able to affect and control the structural and functional properties of the resulting composites in different manners. We found PLGA matrix the most effective in performing this task. The application of the nanotextured 1D morphology and the appropriate balancing of MgO/PLGA interphase interactions with optimal polymer degradation kinetics resulted in superior bactericidal activity of the composites against either planktonic

Indexed as

antimicrobialcontact-based antimicrobial surfacedrug releasemagnesium oxidenanotextured surfacepolymer-matrix composites

Identifiers

PMID34209326
PMCPMC8271688

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.