Evidence map›Paper›PMID 34209322›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Chronic Pulmonary Aspergillosis Situation among Post Tuberculosis Patients in Vietnam: An Observational Study.

Ngoc Thi Bich Nguyen, Huy Le Ngoc, Nhung Viet Nguyen, Luong Van Dinh, Hung Van Nguyen, Huyen Thi Nguyen, David W Denning

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. A Systematic Review of Chronic Pulmonary Aspergillosis Among Patients Treated for Pulmonary Tuberculosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Pooled it
  2. Review
  3. Performance of the LDBioMicrobiology spectrum · 2026
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  15. Chronic pulmonary aspergillosis in tea population of Assam.PLoS neglected tropical diseases · 2025
    Article
  16. Molecular identification and antifungal susceptibility testing ofAfrican journal of laboratory medicine · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Ngoc Thi Bich NguyenVietnam National Lung Hospital, Hanoi 10000, Vietnam.
Huy Le NgocVietnam National Lung Hospital, Hanoi 10000, Vietnam.ORCID 0000-0003-2706-4760
Nhung Viet NguyenVietnam National Lung Hospital, Hanoi 10000, Vietnam.
Luong Van DinhVietnam National Lung Hospital, Hanoi 10000, Vietnam.
Hung Van NguyenVietnam National Lung Hospital, Hanoi 10000, Vietnam.
Huyen Thi NguyenVietnam National Lung Hospital, Hanoi 10000, Vietnam.
David W DenningManchester Academic Health Science Centre, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M23 9LT, UK.ORCID 0000-0001-5626-2251
Hanoi Lung Hospital · VNGlobal Fund to Fight AIDS, Tuberculosis and Malaria · CH

Funding

Medical Research Council MR/P017622/1
6 · The paper itself

Abstract

This study provides a brief view of chronic pulmonary aspergillosis (CPA) in the post-tuberculosis treatment community in Vietnam, a high burden tuberculosis (TB) country. In three months in late 2019, 70 post-TB patients managed at Vietnam National Lung Hospital were enrolled. Of these, 38 (54.3%) had CPA. The male/female ratio was 3/1 (28 males and ten females). CPA patients had a mean age of 59 ± 2.3 years (95%CI 54.4-63.6). The mean Body mass index (BMI) was 19.0 ± 0.5 (18.0-20.0) and 16 of 38 (42.1%) patients had concurrent diseases, the most common of which were chronic obstructive pulmonary disease (COPD) and diabetes. Twenty-six patients (68.4%) developed hemoptysis, 21 (55.3%) breathlessness, and weight loss was seen in 30 (78.9%). Anaemia was seen in 15 (39.5%) and 27 of 38 (71.1%) patients had an elevated C-reactive protein (CRP). The most common radiological findings were multiple cavities (52.6%) and pleural thickening (42.7%), followed by aspergilloma (29.0%) and non-specific infiltrates. There were five of 38 patients (13.2%) with a cavity containing a fungal ball on the chest X-ray, but when the high resolution computed tomography (HRCT) was examined, the number of patients with fungal balls rose to 11 (28.9%). Overall, 34 of 38 (89.5%) cases had an elevated

Indexed as

chronic pulmonary aspergillosisdeveloping countriesprior tuberculosisVietnam

Identifiers

PMID34209322
PMCPMC8307285
OpenAlexW3176410429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.