Evidence map›Paper›PMID 34209249›Full record

ReviewLife (Basel, Switzerland)2021

Machine Learning Protocols in Early Cancer Detection Based on Liquid Biopsy: A Survey.

Linjing Liu, Xingjian Chen, Olutomilayo Olayemi Petinrin, Weitong Zhang, Saifur Rahaman, Zhi-Ri Tang, Ka-Chun Wong

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Linjing LiuDepartment of Computer Science, City University of Hong Kong, Hong Kong, China.ORCID 0000-0002-2366-4593
Xingjian ChenDepartment of Computer Science, City University of Hong Kong, Hong Kong, China.
Olutomilayo Olayemi PetinrinDepartment of Computer Science, City University of Hong Kong, Hong Kong, China.ORCID 0000-0001-8402-9713
Weitong ZhangDepartment of Computer Science, City University of Hong Kong, Hong Kong, China.
Saifur RahamanDepartment of Computer Science, City University of Hong Kong, Hong Kong, China.ORCID 0000-0001-7883-3596
Zhi-Ri TangDepartment of Computer Science, City University of Hong Kong, Hong Kong, China.
Ka-Chun WongDepartment of Computer Science, City University of Hong Kong, Hong Kong, China.ORCID 0000-0001-6062-733X

Funding

grant from City University of Hong Kong CityU 11202219grant from City University of Hong Kong CityU 11203520Research Grants Council of the Hong Kong Special Administrative Region CityU11200218The Government of the Hong Kong Special Administrative Region 07181426
6 · The paper itself

Abstract

With the advances of liquid biopsy technology, there is increasing evidence that body fluid such as blood, urine, and saliva could harbor the potential biomarkers associated with tumor origin. Traditional correlation analysis methods are no longer sufficient to capture the high-resolution complex relationships between biomarkers and cancer subtype heterogeneity. To address the challenge, researchers proposed machine learning techniques with liquid biopsy data to explore the essence of tumor origin together. In this survey, we review the machine learning protocols and provide corresponding code demos for the approaches mentioned. We discuss algorithmic principles and frameworks extensively developed to reveal cancer mechanisms and consider the future prospects in biomarker exploration and cancer diagnostics.

Indexed as

early cancer detectionliquid biopsymachine learning

Identifiers

PMID34209249
PMCPMC8308091

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.