ArticleBrain sciences2021
Discriminant Validity of the WAIS-R Digit Symbol Substitution Test in Subjective Cognitive Decline, Mild Cognitive Impairment (Amnestic Subtype) and Alzheimer's Disease Dementia (ADD) in Greece.
Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Functional magnetic resonance imaging, deep learning, and Alzheimer's disease: A systematic review.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2023Pooled it
- Validity and Reliability of Smartphone-Based Cognitive Assessment in Older Adults.Annals of geriatric medicine and research · 2026Article
- Article
- Effects of Adapted Physical Activity Programs on Body Composition and Sports Performance in a Patient with Parkinson's Disease: A Case Report.Healthcare (Basel, Switzerland) · 2025Article
- Cognitive Function, Diabetes, and Recurrent Falls: From the Health ABC Study.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025Article
- Individual Sleep Problems Are Associated With an Accelerated Decline in Multiple Cognitive Functions in Older Adults.Journal of sleep research · 2025Article
- Predicting severity of cerebral amyloid angiopathy neuropathology: A modeling approach using NACC and ROSMAP data.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Relationship of the TG/HDL Ratio With Cognition Function in Older Adults (≥ 60 Years): A Cross-Sectional Analysis of NHANES 2011-2014.Health science reports · 2025Article
- Multiple chronic conditions and polypharmacy in cognitively unimpaired older adults are associated with subsequent cognitive decline: results from the national alzheimer's coordinating center data.Archives of gerontology and geriatrics · 2025Article
- Pilot study of the Greek Interventional Geriatric Initiative to Prevent Cognitive Impairment and Disability in individuals with subjective cognitive decline: paving the way towards brain health clinics in Greece.Frontiers in psychiatry · 2025Article
- Assessing processing speed and its neural correlates in the three variants of primary progressive aphasia with a non-verbal tablet-based task.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Discriminant Potential of the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) in Greek Older Adults with Subjective Cognitive Decline and Mild Cognitive Impairment.Journal of Alzheimer's disease reports · 2024Article
- Association between cognitive function and body composition in older adults: data from NHANES (1999-2002).Frontiers in aging neuroscience · 2024Article
- Combined association of dietary fibre and cognitive function with all-cause and cause-specific mortality in older adults.Annals of medicine · 2023Article
- Sex differences in the mediating role of chronic inflammation on the association between social isolation and cognitive functioning among older adults in the United States.Psychoneuroendocrinology · 2023Article
- Hypertension, dietary fiber intake, and cognitive function in older adults [from the National Health and Nutrition Examination Survey Data (2011-2014)].Frontiers in nutrition · 2022Article
- Are There Any Cognitive and Behavioral Changes Potentially Related to Quarantine Due to the COVID-19 Pandemic in People with Mild Cognitive Impairment and AD Dementia? A Longitudinal Study.Brain sciences · 2021Article
- Memory Clinics and Day Care Centers in Thessaloniki, Northern Greece: 30 Years of Clinical Practice and Experience.Frontiers in neurology · 2021Review
- Recent contributions to the field of subjective cognitive decline in aging: A literature review.Alzheimer's & dementia (Amsterdam, Netherlands)Review
Corrections and comments
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9 authors.
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Abstract
objectiveThe aim of the current study was to estimate the discriminant potential and validity of the Digit Symbol Substitution Test (DSST) of the WAIS-R in the Greek elderly population meeting criteria for subjective cognitive decline (SCD), mild cognitive impairment (aMCI; amnestic subtype), or Alzheimer's disease dementia (ADD).
methodFour hundred eighty-eight community-dwelling older adults, visitors of the Day Center of Alzheimer Hellas, participated in the study. Two hundred forty-three of them met the criteria for ADD, one hundred eighty-two for aMCI and sixty-three for SCD.
resultsPath analysis indicated that the DSST score is affected by age group, educational level, and diagnostic category, but is not affected by gender. The ROC curve analysis showed that the DSST sum score could perfectly differentiate SCD from ADD patients, whereas test's discriminant potential between aMCI and dementia ADD's subtype was satisfactory. However, DSST was unable to separate the SCD from the aMCI group.
conclusionIt appears that the DSST is unable to separate the SCD from aMCI population. Therefore, the test in question may be insensitive to incipient cognitive decline. On the contrary, the discriminant potential of the DSST as regards SCD and ADD is excellent, while discrimination between aMCI and ADD is good.
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