Evidence map›Paper›PMID 34209170›Full record

ArticleMolecules (Basel, Switzerland)2021

Ahmed S Abu Zaid, Ahmed E Aleissawy, Ibrahim S Yahia, Mahmoud A Yassien, Nadia A Hassouna, Khaled M Aboshanab

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Ahmed S Abu ZaidDepartment of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity St, Abbassia, Cairo P.O. Box 11566, Egypt.
Ahmed E AleissawyDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Organization of African Unity St, Abbassia, Cairo P.O. Box 11566, Egypt.ORCID 0000-0003-1584-7653
Ibrahim S YahiaResearch Center for Advanced Materials Science (RCAMS), King Khalid University, Abha P.O. Box 9004, Saudi Arabia.ORCID 0000-0002-1299-8758
Mahmoud A YassienDepartment of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity St, Abbassia, Cairo P.O. Box 11566, Egypt.
Nadia A HassounaDepartment of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity St, Abbassia, Cairo P.O. Box 11566, Egypt.
Khaled M AboshanabDepartment of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Organization of African Unity St, Abbassia, Cairo P.O. Box 11566, Egypt.ORCID 0000-0002-7608-850X
Ain Shams University · EG

Funding

Research Center for the Advanced Materials Science (RCAMS) at King Khalid University RCAMS/KKU/016-20
6 · The paper itself

Abstract

backgroundThis study aimed to produce, purify, structurally elucidate, and explore the biological activities of metabolites produced by

methodsProduction of cytotoxic metabolites from

resultsBioassay-guided fractionation of the ethyl acetate extract led to the purification of two cytotoxic metabolites, R1 and R2, of reproducible amounts of 5 and 1.5 mg/L, respectively. The structures of R1 and R2 metabolites were identified as β- and γ-rhodomycinone with CD

conclusionsThis is the first report about the production of β- and γ-rhodomycinone, two important scaffolds for synthesis of anticancer drugs, from

Indexed as

Antibiotics, AntineoplasticStreptomyces griseusAnimalsAnthracyclinesBiological ProductsCaco-2 CellsChlorocebus aethiopsHeLa CellsHumansVero CellsAnthracyclinesAntibiotics, AntineoplasticBiological Productsrhodomycinonecytotoxic activityfermentationStreptomyces griseusβ-rhodomycinoneγ-rhodomycinone

Identifiers

PMID34209170
PMCPMC8271628
OpenAlexW3175574911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.