Evidence map›Paper›PMID 34209152›Full record

ReviewAntioxidants (Basel, Switzerland)2021

Beneficial Role of Antioxidant Secondary Metabolites from Medicinal Plants in Maintaining Oral Health.

Manoj Kumar, Suraj Prakash, Radha, Neeraj Kumari, Ashok Pundir, Sneh Punia, Vivek Saurabh, Poonam Choudhary, Sushil Changan, Sangram Dhumal and 7 more

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. A comprehensive review ofBiochemistry and biophysics reports · 2026
    Review
  2. Dentistry journal · 2026
    Review
  3. Article
  4. Article
  5. Phytochemical Profile and Bioactive Potential ofCurrent issues in molecular biology · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Role of Carvacrol in Oral Health: An Overview.Current pharmaceutical design · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Manoj KumarChemical and Biochemical Processing Division, ICAR-Central Institute for Research on Cotton Technology, Mumbai 400019, India.ORCID 0000-0002-4192-6497
Suraj PrakashSchool of Biological and Environmental Sciences, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India.ORCID 0000-0001-5085-3157
RadhaSchool of Biological and Environmental Sciences, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India.
Neeraj KumariSchool of Biological and Environmental Sciences, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India.ORCID 0000-0003-3081-2563
Ashok PundirSchool of Mechanical and Civil Engineering, Shoolini University of Biotechnology and Management Sciences, Solan 173229, India.
Sneh PuniaDepartment of Food, Nutrition, & Packaging Sciences, Clemson University, Clemson, SC 29634, USA.
Vivek SaurabhDivision of Food Science and Postharvest Technology, ICAR-Indian Agricultural Research Institute, New Delhi 110012, India.ORCID 0000-0001-7884-3508
Poonam ChoudharyAgricultural Structure and Environment Control, ICAR-Central Institute of Post-Harvest Engineering and Technology, Ludhiana 141004, India.
Sushil ChanganDivision of Crop Physiology, Biochemistry and Post-Harvest Technology, ICAR-Central Potato Research Institute, Shimla 171001, India.ORCID 0000-0002-7564-7517
Sangram DhumalDivision of Horticulture, RCSM College of Agriculture, Kolhapur 416004, India.
Prakash Chandra PradhanDivision of Agricultural Chemicals, ICAR-Indian Agricultural Research Institute, New Delhi 110012, India.
Omar AlajilDivision of Food Science and Postharvest Technology, ICAR-Indian Agricultural Research Institute, New Delhi 110012, India.ORCID 0000-0001-8396-0856
Sudha SinghDepartment of Vegetable Science, Dr. Y. S. Parmar University of Horticulture and Forestry, Nauni 173230, India.
Neha SharmaDepartment of Biotechnology, Dr. Y. S. Parmar University of Horticulture and Forestry, Nauni 173230, India.
Tamilselvan IlakiyaDepartment of Vegetable Science, Tamil Nadu Agricultural University, Coimbatore 641003, India.ORCID 0000-0001-8894-437X
Surinder SinghDr. S. S. Bhatnagar University Institute of Chemical Engineering and Technology, Panjab University, Chandigarh 160014, India.ORCID 0000-0002-2549-2270
Mohamed MekhemarClinic for Conservative Dentistry and Periodontology, School of Dental Medicine, Christian-Albrecht's University, 24105 Kiel, Germany.ORCID 0000-0003-4294-757X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant-derived phytochemicals have been touted as viable substitutes in a variety of diseases. All over the world, dentists have turned to natural remedies for dental cure due to the negative possessions of certain antibacterial mediators used in dentistry. Antimicrobial and other drugs are currently in use, but they show some side effects. Since ancient times, antioxidant EOs have been used for different ailments and have grown in popularity over time. Several in vitro, in vivo, and clinical trials have shown the safety and effectiveness of antioxidant essential oils (EOs) in oral health obtained from medicinal plants. The current review of literature provides a summary of secondary metabolites, more specifically EOs from 20 most commonly used medicinal plants and their applications in maintaining oral health. Dental caries and periodontal diseases are the most common and preventable global infectious diseases, with diseases of the oral cavity being considered major diseases affecting a person's health. Several clinical studies have shown a connection between oral diseases and oral microbiota. This review discusses the role of antioxidant secondary metabolites in inhibiting the growth of oral pathogens and reducing the formation of dental plaque, and as well as reducing the symptoms of oral diseases. This review article contributes a basic outline of essential oils and their healing actions.

Indexed as

essential oilsmedicinal plantsoral healthphytochemicals

Identifiers

PMID34209152
PMCPMC8300643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.