Evidence map›Paper›PMID 34209118›Full record

ArticleMolecules (Basel, Switzerland)2021

Niclosamide Is Active In Vitro against Mycetoma Pathogens.

Abdelhalim B Mahmoud, Shereen Abd Algaffar, Wendy van de Sande, Sami Khalid, Marcel Kaiser, Pascal Mäser

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Abdelhalim B MahmoudDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, 4051 Basel, Switzerland.ORCID 0000-0003-2500-8909
Shereen Abd AlgaffarFaculty of Pharmacy, University of Khartoum, Khartoum 11111, Sudan.
Wendy van de SandeErasmus Medical Center, Department of Medical Microbiology and Infectious Diseases, 3000 Rotterdam, The Netherlands.
Sami KhalidFaculty of Pharmacy, University of Science and Technology, Omdurman 14411, Sudan.
Marcel KaiserDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, 4051 Basel, Switzerland.ORCID 0000-0003-1785-7302
Pascal MäserDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, 4051 Basel, Switzerland.ORCID 0000-0003-3122-1941
Swiss Tropical and Public Health Institute · CHUniversity of Khartoum · SDErasmus MC · NL

Funding

Emilia Guggenheim-Schnurr Foundation n.a.
6 · The paper itself

Abstract

Redox-active drugs are the mainstay of parasite chemotherapy. To assess their repurposing potential for eumycetoma, we have tested a set of nitroheterocycles and peroxides in vitro against two isolates of

Indexed as

MycetomaActinomaduraAnimalsHumansMadurellaNiclosamideNiclosamideActinomaduradrug repurposingMadurella mycetomatisMMV665807mycetomaniclosamidenitroimidazolesalicylanilide

Identifiers

PMID34209118
PMCPMC8271592
OpenAlexW3174639861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.