Evidence map›Paper›PMID 34209115›Full record

ArticlePolymers2021

Development and Characterization of Novel Cellulose Composites Obtained in 1-Ethyl-3-methylimidazolium Chloride Used as Drug Delivery Systems.

Iuliana Spiridon, Iuliana-Marilena Andrei, Narcis Anghel, Maria Valentina Dinu, Bianca-Iulia Ciubotaru

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Iuliana Spiridon"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica-Vodă 41, 700487 Iasi, Romania.
Iuliana-Marilena Andrei"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica-Vodă 41, 700487 Iasi, Romania.
Narcis Anghel"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica-Vodă 41, 700487 Iasi, Romania.ORCID 0000-0001-5304-0629
Maria Valentina Dinu"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica-Vodă 41, 700487 Iasi, Romania.
Bianca-Iulia Ciubotaru"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica-Vodă 41, 700487 Iasi, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two polysaccharides (cellulose and chitosan) and polyurethane dissolved in 1-ethyl-3-methylimidazolium chloride represented the matrix for the obtainment of new composite formulations comprised of lignin, ferrite-lignin hybrid and ketoconazole. The mechanical performances (Young's modulus and compressive strength) increased with the filler addition. The nature of the filler used in the studied formulations influenced both bioadhesion and mucoadhesion parameters. It was found that the incorporation of lignin and ferrite-lignin hybrid into the matrix has influenced the in vitro rate of ketoconazole release, which is described by the Korsmeyer-Peppas model. All materials exhibited activity against Gram positive (Staphylococcus aureus ATCC 25923) and Gram negative (Escherichia coli ATCC 25922) bacteria.

Indexed as

cellulosechitosancompositesdrug deliveryionic liquidsligninpolyurethane

Identifiers

PMID34209115
PMCPMC8271543
OpenAlexW3173331377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.