Evidence map›Paper›PMID 34208933›Full record

ArticleNutrients2021

The Feasibility and Tolerability of Medium Chain Triglycerides in Women with a Catamenial Seizure Pattern on the Modified Atkins Diet.

Elizabeth A Felton, Bobbie J Henry-Barron, Amanda K Jan, Abigail Shegelman, Kelly Faltersack, Diane Vizthum, Mackenzie C Cervenka

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Elizabeth A FeltonDepartment of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Bobbie J Henry-BarronInstitute for Clinical and Translational Research, Johns Hopkins University School of Medicine, Baltimore, MD 21202, USA.
Amanda K JanDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Abigail ShegelmanDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Kelly FaltersackDepartment of Clinical Nutrition Services, UW Health, Madison, WI 53792, USA.
Diane VizthumInstitute for Clinical and Translational Research, Johns Hopkins University School of Medicine, Baltimore, MD 21202, USA.
Mackenzie C CervenkaDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-4760-857X
Johns Hopkins University · USUniversity of Wisconsin–Madison · USWisconsin Department of Health Services · US

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7M
NCATS NIH HHS UL1 TR002373NCATS NIH HHS UL1 TR003098Vitaflo N/A
6 · The paper itself

Abstract

Ketogenic diet therapy (KDT), particularly modified Atkins diet (MAD), is increasingly recognized as a treatment for adults with epilepsy. Women with epilepsy (WWE) comprise 50% of people with epilepsy and approximately one in three have catamenial epilepsy. The purpose of this study was to determine whether adding a medium chain triglyceride emulsion to MAD to target catamenial seizures was feasible and well-tolerated. This was a prospective two-center study of pre-menopausal WWE with a catamenial seizure pattern on MAD. After a 1-month baseline interval with no changes in treatment, participants consumed betaquik

Indexed as

Diet, High-Protein Low-CarbohydrateAdolescentAdultFeasibility StudiesHumansKetonesMiddle AgedSeizuresTriglyceridesYoung AdultKetonesTriglyceridescatamenialepilepsyketogenic diet therapymedium chain triglyceride (MCT)seizure

Identifiers

PMID34208933
PMCPMC8308415
OpenAlexW3173586225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.