Evidence map›Paper›PMID 34208874›Full record

ReviewDiagnostics (Basel, Switzerland)2021

ACO (Asthma-COPD Overlap) Is Independent from COPD: The Case in Favour.

Peter M A Calverley, Paul Phillip Walker

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The Evolving Landscape of COPD Typization.Medicina (Kaunas, Lithuania) · 2026
    Review
  2. Observational
  3. Article
  4. Understanding the People Excluded from Chronic Obstructive Pulmonary Disease Clinical Trials.American journal of respiratory and critical care medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peter M A CalverleyDepartment of Clinical Science, University of Liverpool, Liverpool L9 7AL, UK.
Paul Phillip WalkerLiverpool University Hospitals Foundation NHS, University of Liverpool, Liverpool L9 7AL, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last decade interest has been shown in people with symptomatic lung disease who have features both of COPD and asthma. In this review we examine how COPD and asthma are defined and examine clinical characteristics of people defined by researchers as having asthma-COPD overlap (ACO). We look at pathological and physiological features along with symptoms and consider the impact of each diagnosis upon therapeutic management. We highlight challenges in the diagnosis and management of airway disease and the various phenotypes that could be part of ACO, in so doing suggesting ways for the clinician to manage patients with features of both asthma and COPD.

Indexed as

asthmaasthma–COPD overlapbronchodilator reversibilityCOPDrespiratory pathophysiology

Identifiers

PMID34208874
PMCPMC8304638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.