Evidence map›Paper›PMID 34208703›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Ozone-Based Eye Drops Activity on Ocular Epithelial Cells and Potential Pathogens Infecting the Front of the Eye.

Roman Paduch, Teresa Urbanik-Sypniewska, Jolanta Kutkowska, Tomasz Chorągiewicz, Anna Matysik-Woźniak, Sandrine Zweifel, Aleksandra Czarnek-Chudzik, Wojciech Załuska, Robert Rejdak, Mario Damiano Toro

Registry-linked trialAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05689996 (Effect of Using of Ozone-based Eye Drops as Adjuvant Therapy in the Management of Microbial Keratitis in Comparison to the Conventional Therapy), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05689996 phase3unknown statusnot on this mapstarted 2023, after this paper: background citation

Effect of Using of Ozone-based Eye Drops as Adjuvant Therapy in the Management of Microbial Keratitis in Comparison to the Conventional Therapy

TypeinterventionalSponsorAssiut UniversityRan2023 to 2023Enrolled40ConditionsKeratitisArmsOzone-Based Agent
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Roman PaduchDepartment of Virology and Immunology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland.ORCID 0000-0001-9779-7252
Teresa Urbanik-SypniewskaDepartment of Genetics and Microbiology, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland.
Jolanta KutkowskaDepartment of Genetics and Microbiology, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland.ORCID 0000-0002-3307-591X
Tomasz ChorągiewiczDepartment of General and Pediatric Ophthalmology, Medical University of Lublin, Chmielna 1, 20-079 Lublin, Poland.
Anna Matysik-WoźniakDepartment of General and Pediatric Ophthalmology, Medical University of Lublin, Chmielna 1, 20-079 Lublin, Poland.ORCID 0000-0003-0865-6541
Sandrine ZweifelDepartment of Ophthalmology, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0001-7431-1774
Aleksandra Czarnek-ChudzikDepartment of Diagnostic and Microsurgery of Glaucoma, Medical University of Lublin, Chmielna 1, 20-079 Lublin, Poland.
Wojciech ZałuskaDepartment of Nephrology, Medical University of Lublin, Jaczewskiego 8, 20-090 Lublin, Poland.ORCID 0000-0001-6043-3236
Robert RejdakDepartment of General and Pediatric Ophthalmology, Medical University of Lublin, Chmielna 1, 20-079 Lublin, Poland.ORCID 0000-0003-3321-2723
Mario Damiano ToroDepartment of General and Pediatric Ophthalmology, Medical University of Lublin, Chmielna 1, 20-079 Lublin, Poland.ORCID 0000-0001-7152-2613

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Confirmation of the biological effectiveness of new ophthalmic preparations introduced in the market is an important element in maintaining the safety of using this type of medications. This study aimed to investigate the activity of Ozodrop

Indexed as

bacteriacell culture in vitroconjunctival epitheliumcorneal epitheliumozone-based dropstoxicity

Identifiers

PMID34208703
PMCPMC8235398

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.