Evidence map›Paper›PMID 34208647›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis and Antiviral Evaluation of Nucleoside Analogues Bearing One Pyrimidine Moiety and Two D-Ribofuranosyl Residues.

Olga V Andreeva, Bulat F Garifullin, Vladimir V Zarubaev, Alexander V Slita, Iana L Yesaulkova, Alexandrina S Volobueva, Mayya G Belenok, Maria A Man'kova, Liliya F Saifina, Marina M Shulaeva and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Olga V AndreevaArbuzov Institute of Organic and Physical Chemistry, Federal Research Center "Kazan Scientific Center of Russian Academy of Sciences", Arbuzov 8, 420088 Kazan, Russia.ORCID 0000-0001-5518-8395
Bulat F GarifullinArbuzov Institute of Organic and Physical Chemistry, Federal Research Center "Kazan Scientific Center of Russian Academy of Sciences", Arbuzov 8, 420088 Kazan, Russia.
Vladimir V ZarubaevPasteur Institute of Epidemiology and Microbiology, Mira 14, 197101 Saint Petersburg, Russia.ORCID 0000-0002-5224-3771
Alexander V SlitaPasteur Institute of Epidemiology and Microbiology, Mira 14, 197101 Saint Petersburg, Russia.ORCID 0000-0001-8229-0715
Iana L YesaulkovaPasteur Institute of Epidemiology and Microbiology, Mira 14, 197101 Saint Petersburg, Russia.
Alexandrina S VolobuevaPasteur Institute of Epidemiology and Microbiology, Mira 14, 197101 Saint Petersburg, Russia.
Mayya G BelenokArbuzov Institute of Organic and Physical Chemistry, Federal Research Center "Kazan Scientific Center of Russian Academy of Sciences", Arbuzov 8, 420088 Kazan, Russia.
Maria A Man'kovaArbuzov Institute of Organic and Physical Chemistry, Federal Research Center "Kazan Scientific Center of Russian Academy of Sciences", Arbuzov 8, 420088 Kazan, Russia.
Liliya F SaifinaArbuzov Institute of Organic and Physical Chemistry, Federal Research Center "Kazan Scientific Center of Russian Academy of Sciences", Arbuzov 8, 420088 Kazan, Russia.
Marina M ShulaevaArbuzov Institute of Organic and Physical Chemistry, Federal Research Center "Kazan Scientific Center of Russian Academy of Sciences", Arbuzov 8, 420088 Kazan, Russia.
Alexandra D VoloshinaArbuzov Institute of Organic and Physical Chemistry, Federal Research Center "Kazan Scientific Center of Russian Academy of Sciences", Arbuzov 8, 420088 Kazan, Russia.
Anna P LyubinaArbuzov Institute of Organic and Physical Chemistry, Federal Research Center "Kazan Scientific Center of Russian Academy of Sciences", Arbuzov 8, 420088 Kazan, Russia.
Vyacheslav E SemenovArbuzov Institute of Organic and Physical Chemistry, Federal Research Center "Kazan Scientific Center of Russian Academy of Sciences", Arbuzov 8, 420088 Kazan, Russia.ORCID 0000-0001-8350-2433
Vladimir E KataevArbuzov Institute of Organic and Physical Chemistry, Federal Research Center "Kazan Scientific Center of Russian Academy of Sciences", Arbuzov 8, 420088 Kazan, Russia.

Funding

Ministry of Education and Science of the Russian Federation AAAA-A18-118040390114-8Russian Science Foundation 19-13-00003
6 · The paper itself

Abstract

A series of 1,2,3-triazolyl nucleoside analogues in which 1,2,3-triazol-4-yl-β-d-ribofuranosyl fragments are attached via polymethylene linkers to both nitrogen atoms of the heterocycle moiety (uracil, 6-methyluracil, thymine, quinazoline-2,4-dione, alloxazine) or to the C-5 and

Indexed as

Antiviral AgentsClick ChemistryHumansInfluenza A Virus, H1N1 SubtypeMolecular Docking SimulationNucleosidesPyrimidinesRNA-Dependent RNA PolymeraseStructure-Activity RelationshipAntiviral AgentsNucleosidesPyrimidinesRNA-Dependent RNA Polymerase1,2,3-triazoleantiviralsclick chemistrycoxsackievirusinfluenza virusnucleoside analogues

Identifiers

PMID34208647
PMCPMC8234143

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.