Evidence map›Paper›PMID 34208565›Full record

ArticleCells2021

Statistical Approach to Incorporating Experimental Variability into a Mathematical Model of the Voltage-Gated Na

Daniel Gratz, Alexander J Winkle, Seth H Weinberg, Thomas J Hund

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Daniel GratzDepartment of Biomedical Engineering, College of Engineering, The Ohio State University, Columbus, OH 43210, USA.
Alexander J WinkleDepartment of Biomedical Engineering, College of Engineering, The Ohio State University, Columbus, OH 43210, USA.
Seth H WeinbergDepartment of Biomedical Engineering, College of Engineering, The Ohio State University, Columbus, OH 43210, USA.
Thomas J HundDepartment of Biomedical Engineering, College of Engineering, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-9957-7306
The Ohio State University Wexner Medical Center · US

Funding

Defining novel mechanisms for regulation of atrial INa and arrhythmiasR01HL134824 · NHLBI · OHIO STATE UNIVERSITY · PI HUND, THOMAS JEFFREY, MOHLER, PETER J. · 2017 to 2020
$3.0M
Role of TREK-1 in modulating cardiac excitability and arrhythmiaR01HL156652 · NHLBI · OHIO STATE UNIVERSITY · PI HUND, THOMAS JEFFREY · 2021 to 2024
$1.7M
Spectrin-based regulation of cardiac remodeling and heart failureR01HL135096 · NHLBI · OHIO STATE UNIVERSITY · PI HUND, THOMAS JEFFREY · 2017 to 2020
$1.6M
NIH HHS R01HL134824NIH HHS R01HL135096NIH HHS R01HL156652
6 · The paper itself

Abstract

The voltage-gated Na

Indexed as

Computer SimulationModels, TheoreticalAction PotentialsAtrial FibrillationAtrial FunctionBayes TheoremHumansMyocytes, CardiacNAV1.5 Voltage-Gated Sodium ChannelNAV1.5 Voltage-Gated Sodium ChannelSCN5A protein, humanarrhythmiaatrial fibrillationBayesian statisticscomputational modelelectrophysiologyvoltage-gated sodium channel

Identifiers

PMID34208565
PMCPMC8234464
OpenAlexW3166338065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.