Evidence map›Paper›PMID 34208470›Full record

ReviewJournal of clinical medicine2021

COVID-19 and Delayed Cerebral Ischemia-More in Common Than First Meets the Eye.

Pervinder Bhogal, Levansri Makalanda, Ameer E Hassan, Dave Fiorella, Tommy Andersson, Muhammad Ahmad, Hansjörg Bäzner, Ounali Jaffer, Hans Henkes

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Pervinder BhogalDepartment of Interventional Neuroradiology, The Royal London Hospital, Barts NHS Trust, Whitechapel Road, Whitechapel, London E1 1BB, UK.
Levansri MakalandaDepartment of Interventional Neuroradiology, The Royal London Hospital, Barts NHS Trust, Whitechapel Road, Whitechapel, London E1 1BB, UK.ORCID 0000-0001-6637-9293
Ameer E HassanDepartments of Neurology and Radiology, University of Texas Rio Grande Valley, Harlingen, TX 78550, USA.ORCID 0000-0002-7148-7616
Dave FiorellaDepartment of Neurosurgery, Stony Brook University Hospital, Stony Brook, NY 11794, USA.
Tommy AnderssonDepartment of Interventional Neuroradiology, The Karolinska University Hospital, 171 76 Stockholm, Sweden.ORCID 0000-0001-8202-7829
Muhammad Ahmad4C Pharma Solutions LLC, Piscataway, NJ 08854, USA.
Hansjörg BäznerDepartment of Neurology, Klinikum Stuttgart, 70174 Stuttgart, Germany.
Ounali JafferDepartment of Interventional Radiology, The Royal London Hospital, Barts NHS Trust, Whitechapel Road, Whitechapel, London E1 1BB, UK.
Hans HenkesDepartment of Neuroradiology, Klinikum Stuttgart, 70174 Stuttgart, Germany.ORCID 0000-0002-6534-036X
Royal London Hospital · GBKlinikum Stuttgart · DEKarolinska University Hospital · SEStony Brook University Hospital · USThe University of Texas Rio Grande Valley · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the arrival of the global COVID-19 pandemic scientists around the world have been working to understand the pathological mechanisms resulting from infection. There has gradually been an understanding that COVID-19 triggers a widespread endotheliopathy and that this can result in a widespread thrombosis and in particular a microthrombosis. The mechanisms involved in the microthrombosis are not confined to infection and there is evidence that patients with aneurysmal sub-arachnoid haemorrhage (SAH) also suffer from an endotheliopathy and microthrombosis. In this article we attempt to shed light on similarities in the underlying processes involved in both diseases and suggest potential treatment options.

Indexed as

COVID-19delayed cerebral ischemiamicrothrombosissubarachnoid haemorrhage

Identifiers

PMID34208470
PMCPMC8233948
OpenAlexW3170966247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.