Evidence map›Paper›PMID 34208452›Full record

ArticleCells2021

ABHD4-Regulating RNA Panel: Novel Biomarkers in Acute Coronary Syndrome Diagnosis.

Sara H A Agwa, Sherif Samir Elzahwy, Mahmoud Shawky El Meteini, Hesham Elghazaly, Maha Saad, Aya M Abd Elsamee, Rania Shamekh, Marwa Matboli

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sara H A AgwaClinical Pathology and Molecular Genomics Unit, Medical Ain Shams Research Institute (MASRI), Faculty of Medicine, Ain Shams University, Cairo 11382, Egypt.ORCID 0000-0002-2382-0189
Sherif Samir ElzahwyCardiovascular Medicine Department, Faculty of Medicine, Ain Shams University, Cairo 11382, Egypt.
Mahmoud Shawky El MeteiniDepartment of General Surgery, The School of Medicine, University of Ain Shams, Cairo 11382, Egypt.
Hesham ElghazalyOncology Department, Medical Ain Shams Research Institute (MASRI), Faculty of Medicine, Ain Shams University, Cairo 11382, Egypt.
Maha SaadBiochemistry Department, Faculty of Medicine, Modern University for Technology and Information, Cairo 11382, Egypt.
Aya M Abd ElsameeBiochemistry and Molecular Genomics Unit, Medical Ain Shams Research Institute (MASRI), Faculty of Medicine, Ain Shams University, Cairo 11382, Egypt.ORCID 0000-0003-4799-3954
Rania ShamekhDepartment of Pathology, University of South Florida, Tampa, FL 33620, USA.
Marwa MatboliMedicinal Biochemistry and Molecular Biology Department, Faculty of Medicine, Ain Shams University, Cairo 11382, Egypt.
Ain Shams University · EGModern University for Information and Technology · EGUniversity of South Florida · US

Funding

Academy of Science and Technology jesor_20173054
6 · The paper itself

Abstract

backgroundAcute coronary syndrome (ACS) is a major cause of death all over the world. STEMI represents a type of myocardial infarction with acute ST elevation. We aimed to assess the predictive power of potential RNA panel expression in acute coronary syndrome.

methodWe used in silico data analysis to retrieve RNAs related to glycerophospholipid metabolism dysregulation and specific to ACS that results in the selection of Alpha/Beta hydrolase fold domain4 (

resultsThe study data showed significant down regulation in the expression of the serum levels of

conclusionCollectively,

Indexed as

Gene Expression RegulationLysophospholipaseAcute Coronary SyndromeBiomarkersHumansMicroRNAsRNA, Long NoncodingRNA, MessengerABHD4 protein, humanBiomarkersLysophospholipaseMicroRNAsRNA, Long NoncodingRNA, Messengeracute coronary syndromebioinformaticsdiagnosisglycerophospholipidRNAserumtroponin

Identifiers

PMID34208452
PMCPMC8235602
OpenAlexW3170289509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.